Yin Cheng

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In KDD procedure, to fill in missing data typically requires a very large investment of time and energy-often 80% to 90% of a data analysis project is spent in making the data reliable enough so that the results can be trustful. In this paper, we propose a SVM regression based algorithm for filling in missing data, i.e. set the decision attribute (output(More)
Huntington's disease-like-2 (HDL2) is a phenocopy of Huntington's disease caused by CTG/CAG repeat expansion at the Junctophilin-3 (JPH3) locus. The mechanisms underlying HDL2 pathogenesis remain unclear. Here we developed a BAC transgenic mouse model of HDL2 (BAC-HDL2) that exhibits progressive motor deficits, selective neurodegenerative pathology, and(More)
We are now witnessing a new genomic revolution due to the arrival and continued advancements in the next-generation high-throughput sequencing technologies, which encompass sequencing by synthesis including fluorescent in situ sequencing (FISSEQ) and pyrosequencing, sequencing by ligation including using polony amplification and supported oligonucleotide(More)
Spinal cord injury (SCI) is considered incurable because axonal regeneration in the central nervous system (CNS) is extremely challenging, due to harsh CNS injury environment and weak intrinsic regeneration capability of CNS neurons. We discovered that neurotrophin-3 (NT3)-loaded chitosan provided an excellent microenvironment to facilitate nerve growth,(More)
Disturbances in the sleep/wake cycle are prevalent in patients with Rett syndrome (RTT). We sought to determine whether the circadian system is disrupted in a RTT model, Mecp2(-/y) mice. We found that MeCP2 mutants showed decreased strength and precision of daily rhythms of activity coupled with extremely fragmented sleep. The central circadian clock(More)
Video based 3D reconstruction of human motion plays an important role in many applications. We implement a system that robustly reconstructs 3D human motion from markerless videos taken by a single camera. Our system only requires a desktop PC and a mainstream camera, and doesn't involve complex camera calibration, making it easy to implement and widely(More)
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