Yilin Zhang

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In this work, we present a new optical routing framework, <i>O-Router</i> for future low-power on-chip optical interconnect integration utilizing silicon compatible nano-photonic devices. We formulate the optical layer routing problem as the minimization of total on-chip optical modulator cost (laser power consumption) with Integer Linear Programming(More)
This paper presents a class of hydration monitor that uses ultrathin, stretchable sheets with arrays of embedded impedance sensors for precise measurement and spatially multiplexed mapping. The devices contain miniaturized capacitive electrodes arranged in a matrix format, capable of integration with skin in a conformal, intimate manner due to the overall(More)
microRNA 21 (miR-21) has been demonstrated to be significantly elevated in many types of cancers, including the hepatocellular carcinoma (HCC). In the present study, we investigated the role of miR-21 in HCC by identifying its novel targets, as well as its underlying molecular mechanism. The expression of mitogen-activated protein kinase-kinase 3 (MAP2K3)(More)
In this paper, we study an often overlooked but very important and practical problem of building Buffering-aware Over-the-Block rectilinear Steiner minimum tree (BOB-RSMT). In most previous works, the routing resources over the IP blocks were simply treated as routing blockages, resulting in significant waste of routing resources on higher metal layers not(More)
The tumour microenvironment contributes to cancer metastasis and drug resistance. However, most high throughput screening (HTS) assays for drug discovery use cancer cells grown in monolayers. Here we show that a multilayered culture containing primary human fibroblasts, mesothelial cells and extracellular matrix can be adapted into a reliable 384- and(More)
—In this paper, we propose a new global router, BOB-Router, endowed with the ability to use over-the-block routing resources to the greatest extent in addition to traditional routing concepts of minimizing wirelength, via count and overflow. In previous global routing formulations, the routing resources over the IP blocks were either dealt as routing(More)
In this paper, we study a fundamental and crucial problem of building timing-driven over-the-block rectilinear Steiner tree (TOB-RST) with pre-buffering and slew constraints. We pre-characterize the tree topology and buffer distribution to provide accurate timing information for our final RST construction. In most previous work, the routing resources over(More)