Yilin Cheng

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Systemic lupus erythematosus (SLE) is a multi-system autoimmune disease with complex genetic inheritance. IKZF1 was established as a new susceptibility gene for SLE in a recent genome-wide association study (GWAS) in Chinese Han population. In order to examine whether expression levels of IKZF1 contribute to the pathogenesis of SLE, we estimated IKZF1 mRNA(More)
BACKGROUND Chromosomal region 16p13 has been reported to harbour variants associated with several autoimmune diseases, including type I diabetes, rheumatoid arthritis and multiple sclerosis. OBJECTIVE To test whether variants in the 16p13 region are also associated with systemic lupus erythematosus (SLE) by performing a candidate locus study in the(More)
Porous three-dimensional graphene (3DG) prepared by chemical vapor deposition, was utilized as a matrix to support nanoscale zero-valent iron (nZVI) particles. The strategies to manipulate the morphology, distribution and size of nZVI particles on the 3DG support were demonstrated. The immobilized nZVI particles with a size of 100 nm and dense deposition(More)
One of the key challenges in engineering neural tissues for cell-based therapies is to develop a biocompatible scaffold material to direct neural stem cell (NSC) behaviors. One great advantage for a scaffold would be to induce NSC migration toward pathological sites during regeneration and repair. In particular, the inflammatory responses in the(More)
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