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BACKGROUND Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant syndrome. The National Cancer Institute (NCI) has recommended the Revised Bethesda guidelines for screening HNPCC. There has been a great deal of research on the value of these tests in other countries. However, literature about the Chinese population is scarce. Our(More)
BACKGROUND Colorectal carcinogenesis is believed to be a multi-stage process that originates with a localized adenoma, which linearly progresses to an intra-mucosal carcinoma, to an invasive lesion, and finally to metastatic cancer. This progression model is supported by tissue culture and animal model studies, but it is difficult to reconcile with several(More)
BACKGROUND Our previous studies of human breast and prostate cancer have shown that aberrant immune cell infiltration is associated with focal tumor capsule disruption and tumor cell budding that facilitate invasion and metastasis. Our current study attempted to determine whether aberrant immune cell infiltration would have similar impact on colorectal(More)
With the extensive use of diet pills which contain stimulating laxative, the incidence of cathartic colon shows an upward tendency year by year. Ca-thartic colon is clinically a common functional stubborn constipation as the main characteristics of colon power weakening and long-term use of stimulating laxative, at the same time it is an important type of(More)
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