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Introduction: Measuring white matter perfusion using arterial spin labeling (ASL) MRI is challenging for various reasons [1]: perfusion in white matter is low compared to that in gray matter, resulting in a lower intrinsic signal to noise ratio (SNR); the relative low resolution of ASL MRI images causes partial volume effects and overestimation of white(More)
Kinetic analysis of walking requires joint kinematics and ground reaction force (GRF) measurement, which are typically obtained from a force plate. GRF is difficult to measure in certain cases such as slope walking, stair climbing, and track running. Nevertheless, estimating GRF continues to be of great interest for simulating human walking. The purpose of(More)
A time course and its power spectrum measured from a single voxel (upper row) and those from the sinusoidal component at the frequency of the multiphase modulation (lower row). FIG. 2. An example of estimates of ASL signal, phase tracking error, and baseline signal with the two estimation methods. Table 1. Comparisons of mean gray matter CBF and the(More)
Human dynamic models have been used to estimate joint kinetics during various activities. Kinetics estimation is in demand in sports and clinical applications where data on external forces, such as the ground reaction force (GRF), are not available. The purpose of this study was to estimate the GRF during gait by utilizing distance- and velocity-dependent(More)
Joint contact forces measured with instrumented knee implants have not only revealed general patterns of joint loading but also showed individual variations that could be due to differences in anatomy and joint kinematics. Musculoskeletal human models for dynamic simulation have been utilized to understand body kinetics including joint moments, muscle(More)
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