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The higher failure rate of total hip arthroplasty (THA) in young, active patients remains a challenge for surgeons. Recently, larger-diameter femoral heads combined with an alumina matrix composite ceramic (BIOLOX Delta; CeramTec AG, Plochingen, Germany) articulation was developed to improve implant longevity and meet patients' activity demands while(More)
OBJECTIVE The aim of this study was to evaluate the clinical and radiological outcomes and complications of total hip arthroplasty (THA) using the collum femoris preserving (CFP) prosthesis. METHODS The study included the 142 hips of 125 patients (mean age: 50 years; range: 38 to 60 years) who underwent THA with CFP prosthesis between January 2004 and(More)
Modular femoral prostheses can provide independent distal fixation and intraoperative flexibility and are being used increasingly, especially in patients with proximal femoral bone defects. This retrospective clinical study evaluated whether modular prostheses were effective and reliable implants for femoral revision. This case series consisted of 58(More)
The aim of this study was to evaluate the effectiveness associated with the use of the cementless femoral revision in patients with a previous cemented prosthesis. This study reviewed 92 revision femoral stem performed by a single senior surgeon between January 2006 and December 2012 at our institution. All patients complained of unbearable pain before(More)
The use of total hip arthroplasty (THA) to treat advanced tuberculous arthritis, particularly during the active phase, is challenging. The aim of this study was to evaluate the efficacy of cementless THA for advanced hip joint tuberculosis. This study reviewed 32 patients (mean age at surgery, 49.4 years [range, 24–79 years]) who underwent cementless THA(More)
BACKGROUND We conducted a systematic review and meta-analysis to obtain a reliable estimation of the prevalence of osteoporosis in China and to characterize its epidemiology. METHODS We identified relevant studies via a search of literature published from 2003 to October 2015 in the PubMed, Web of Science, China National Knowledge Infrastructure, Wanfang(More)
MicroRNAs (miRs) have been implicated in tumorigenesis through inhibition of the expression of their target genes at post-transcriptional levels. miR-124 has been found to be downregulated in many malignant tumors including osteosarcoma (OS). However, the detailed mechanism of miR-124 in the regulation of OS malignant phenotypes remains largely unclear.(More)
Ankylosing spondylitis is a chronic inflammatory rheumatic disease, which is characterized by inflammation of the spine and the sacroiliac joints. To date, the disease etiology remains unclear. In the present study, the correlation of T lymphocyte subset changes with the progression of ankylosing spondylitis was investigated. A total of 55 patients with(More)
Osteosarcoma (OS), a malignant mesenchymal sarcoma, is the most frequent primary bone tumor, with a peak incidence in young children and adolescents. The downregulation of microRNA‑145 (miRNA/miR‑145) has previously been identified to be associated with the aggressiveness and metastasis of OS. However, the detailed regulatory mechanism by which miR‑145(More)
OBJECTIVE This study aims to investigate the biomechanical effect of posterior cruciate ligament (PCL) rupture on lateral meniscus. METHOD The stresses of anterior horn, caudomedial part and posterior horn of lateral meniscus in cadaveric knees were recorded when the knee joints were loaded 200 to 1000 N at 0, 30, 60 and 90° of flexion. Twelve knees were(More)