Yih Kai Chan

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OBJECTIVES The goal of this study was to make a head-to-head comparison of 2 common forms of multidisciplinary chronic heart failure (CHF) management. BACKGROUND Although direct patient contact appears to be best in delivering CHF management overall, the precise form to optimize health outcomes is less clear. METHODS This prospective, multicenter(More)
Periodontal bio-repositories, which allow banking of clinically validated human data and biological samples, provide an opportunity to derive biomarkers for periodontal diagnosis, prognosis and therapeutic activities which are expected to improve patient management. This article presents the establishing of the Malaysian Periodontal Database and Biobank(More)
BACKGROUND Primary peritoneal malignant mixed Müllerian tumors (MMMTs) are rarely reported in the literature. METHODS The clinical, pathologic, and immunohistochemical features of five cases of MMMT of female peritoneum were analyzed. The tumors were also investigated for expression of hormone receptors, specific BRCA-1 mutations, and clonality. RESULTS(More)
BACKGROUND Frequent readmissions are a hallmark of chronic heart failure (CHF). We sought to develop an absolute risk prediction model for unplanned cardiovascular readmissions following hospitalisation for CHF. METHODS An inception cohort was obtained from the WHICH? trial, a prospective, multi-centre randomised controlled trial which was a head-to-head(More)
Blood is collected during animal experimentation to measure haematological and metabolic parameters. It cannot be assumed that circulating blood has the same composition irrespective of its location, and indeed, differences in the composition of blood sampled from the arterial and venous compartments have been reported. Here we investigated whether blood(More)
BACKGROUND Patients are increasingly being admitted with chronic atrial fibrillation, and disease-specific management might reduce recurrent admissions and prolong survival. However, evidence is scant to support the application of this therapeutic approach. We aimed to assess SAFETY--a management strategy that is specific to atrial fibrillation. METHODS(More)
This paper presents an evaluation of the logistic and Cox regression models for a prospective study when the outcome is binary and is determined in all patients after a fixed period of time. The similarities and differences between the regression coefficients and test statistics are given for the two-sample case. Extension of results to the multivariate(More)