Yiguang Chen

Learn More
OBJECTIVE To understand the diversity of cultivable bacteria isolated from a sea anemone collected from the coastal water of the Naozbou island in the Leizhou Bay on South China Sea. METHODS Bacteria were isolated from a sea anemone by using conventional culture-dependent method and investigated by using phylogenetic analysis based on 165 rRNA gene(More)
Three metabolites named phomopsin A (1), B (2) and C (3), together with two known compounds cytosporone B (4) and C (5), were isolated from the mangrove endophytic fungus, Phomopsis sp. ZSU-H76 obtained from the South China Sea. Their structures were elucidated by spectroscopic methods, mainly by 1D and 2D NMR spectroscopic techniques. The medium-sized(More)
OBJECTIVE To investigate the diversity of cultivable halophilic and halotolerant bacteria isolated from ordinary non-saline soil samples collected from Xiaoxi National Natural Reserve (28 degrees 42' 15"-28 degrees 53' 15" N, 110 degrees 6' 50"-110 degrees 21' 35" E), Hunan Province, China. METHODS Bacterial strains were isolated from the samples by using(More)
OBJECTIVE To investigate the diversity of culturable bacteria isolated from the sea urchin Hemicentrotus pulcherrimus collected from a tidal flat of Naozhou Island (20 degrees 52'N - 20 degrees 56'N 110 degrees 33'E - 110 degrees 38'E), Leizhou Bay, South China Sea, China. METHODS Bacteria were isolated from the sample by using conventional(More)
The structure elucidations and complete (1)H and (13)C NMR assignments are reported for two new natural products: 3-benzylidene-8,8a-dihydroxy-2-methyl-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione(1) and 4-hydroxy-6-(hydroxy-phenyl-methyl)-N-(3-methyl-butyryl)-nicotinamide (2). Both of these secondary metabolites were isolated from the fermentation medium of(More)
A new isochroman, (3R,4S)-3,4-dihydro-4,5,8-trihydroxy-3-methylisocoumarin (1), and two known compounds were isolated from the marine fungus Phomopsis sp. (No. ZH-111). Their structures were determined by spectroscopic methods, mainly 1D and 2D NMR. Preliminary pharmacological test revealed that compound 1 and exumolide A (3) can accelerate the growth of(More)
OBJECTIVE To isolate new actinomycetes for discovering compounds of pharmaceutical importance. METHODS We collected 280 soil samples from virgin forest in Wuling Mountain. In total 1134 actinomycetes were isolated by culture-dependent method. Of them 30 strains were selected and then characterized by phylogenetic analysis based on sequences of 16S rRNA(More)
The structure elucidations and complete (1)H and (13)C NMR assignments are reported for three new anthraquinone derivatives: Fusaquinon A (1), B (2), and C (3) isolated from the fermentation medium of the marine fungus Fusarium sp. (No. ZH-210). HREIMS, Fourier transform infrared absorption spectrometry (FT-IR), NMR experiments including gCOSY, gHMQC,(More)
A new indene derivative named phomoindene A (1) and four known compounds were isolated from the marine fungus Phomopsis sp. (No. GX7-4A). Their structures were determined by spectroscopic methods, mainly 1D and 2D NMR. Preliminary pharmacological tests revealed that phomoindene A exhibited little cytotoxic activity towards KB, KBv 200, and MCF-7 cell lines.