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The reduction of hippocampal volume remains controversial in depression because of the variability among individuals in clinical studies. Here, a reliable experimental rat model of depression, established by chronic unpredictable mild stress (CUMS), was used. Thirty rats were randomly divided into two groups (CUMS group and control group). Hippocampal(More)
BACKGROUND Limbic structural changes have been found in people with post-traumatic stress disorder (PTSD). However, the results were controversial, and no study has examined the hippocampal and amygdala volume changes in parents with or without PTSD who had lost their only child and could no longer conceive in China. METHODS Hippocampal and amygdala(More)
BACKGROUND The volumetry of the hippocampal subregion may provide additional information in the early investigation of amnestic mild cognitive impairment (aMCI) and the T2 signal intensity (T2-SI) of the hippocampal subregion has not been well studied quantitatively by magnetic resonance imaging (MRI) in aMCI. METHODS Using combined MRI-based hippocampal(More)
Investigating hippocampal subfields may provide new and important insights into the pathophysiology of posttraumatic stress disorder (PTSD). However, no study has examined the hippocampal subfield volume changes in parents with or without PTSD who had lost their only child and could no longer conceive in China. Fifty-seven parents with PTSD (PTSD+), 11(More)
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