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Low rates of angiotensin II (Ang II) infusion raise blood pressure, renal vascular resistance (RVR), NADPH oxidase activity, and superoxide. We tested the hypothesis that these effects are ameliorated by extracellular superoxide dismutase (EC-SOD). EC-SOD knockout (-/-) and wild type (+/+) mice were equipped with blood pressure telemeters and infused(More)
This paper studies the problem of applying multiple-input multiple-output (MIMO) radar techniques for lesion classification in ultrawideband (UWB) breast imaging. Ongoing work on this topic has suggested that benign and malignant masses, which usually possess remarkable architectural differences, could be distinguished by exploiting their(More)
We present a new approach to the problem of detecting cancerous tissues at low-to-medium signal-to-noise ratios (SNRs) in an interference-prone biological medium, where the dielectric properties of the surrounding heterogeneous healthy tissues are comparable to those of the tumors. Suppose that microwave contrast agents, such as microbubbles or(More)
BACKGROUND MicroRNA (miRNA) is a small, non-coding RNA molecule which plays a role in the carcinogenesis and progression of cancers. Abnormal expression of miRNA in plasma has been found in some patients with malignant tumors. MATERIAL AND METHODS This study was conducted to investigate the expression of miRNA-30a in plasma of patients with non-small cell(More)
Miner1 is a redox-active 2Fe2S cluster protein. Mutations in Miner1 result in Wolfram Syndrome, a metabolic disease associated with diabetes, blindness, deafness, and a shortened lifespan. Embryonic fibroblasts from Miner1(-/-) mice displayed ER stress and showed hallmarks of the unfolded protein response. In addition, loss of Miner1 caused a depletion of(More)