Yi-jin Wang

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Nogo-66 is a 66-amino-acid-residue extracellular domain of Nogo-A, which plays a key role in inhibition neurite outgrowth of central nervous system through binding to the Nogo-66 receptor (NgR) expressed on the neuron. Recent studies have confirmed that NgR is also expressed on the surface of macrophages/microglia in multiple sclerosis, but its biological(More)
Pancreatic cancer (PCC) is one of the most difficult cancers to treat and the 10th leading cause of cancer-related death in worldwide. Studies have demonstrated that the tetraspanin 1 (Tspan1) is overexpressed in various cancers and may be a potential therapeutic strategy for the treatment of different cancers. However, the possible role of Tspan1 in PCC is(More)
OBJECTIVE To investigate the mechanical characteristics of new anatomic plate of distal tibia from view of biomechanics. METHODS Twelve fresh adult moist ankle specimens were randomly divided into four block groups (every group had 3 specimens), 3 tibial specimens as a normal control (normal group N), 9 specimens were resulted in unstable distal tibial(More)
OBJECTIVE To compare the cervical stabilities of transarticular screw fixation alone, and transarticular screw and plate fixation system. METHODS Twelve specimens of cervical vertebra containing C2-T1 were obtained from human cadaver. The three-column instability model was made at C4.5 and C5.6 levels. The specimens were stabilized with transarticular(More)
OBJECTIVE To recognize the effect of minimal-invasive dynamic hip screw (MIDHS) on the treatment of intertrochanteric fracture of the hip by biomechanical test and preliminary clinical application. METHODS Ten artifical made intertrochanteric fractures of femoral specimen from five cadavers were divided into two groups randomly. The fractures in first(More)
OBJECTIVE To observe the influence of the fusion of bone graft in spine of rabbits which were treated with lower intensity ultrasound. METHODS Forty 12-month-old rabbits were made to be the models of bone graft in post-lateral between two homonymy processus transverses in lumbar, and divided into treatment group (B) and control group (A) randomly. Twenty(More)
A bioinformatics analysis was carried out to compare nucleotide and protein sequences of Hoxd13 (homeobox D13), a gene involved in cloacal septum development. Based on structure of cloacal septum, 10 vertebrate species were selected, among which 6 have cloacal septum development, whilst other 4 have persistent cloacal structure. Alignment of protein(More)
OBJECTIVE To compare statics characteristics between anterior transpedicular screws (ATPS) system and vertebral body screws (VBS) system in lower cervical spine. METHODS Sixteen fresh cervical specimens were collected and dissected into 32 different units (functional spinal unit, FSU), 8 units in C3,4, C4,5, C5,6 and C6,7 each. The subjects were randomly(More)
OBJECTIVE To compare the biomechanics of three internal fixations for distal femoral fractures,and to choose suitable clinical internal fixation according to experimental date. METHODS The fracture models of femoral condydle were made on 12 fresh cadaver femurs (C1 type of AO classification). The fractures were fixed by supracondylar intramedullary(More)
OBJECTIVE To evaluate the biomechanical personality of the sacroiliac anatomy type Bar-plate system (SABP), which was of fixation usage to the fracture or dislocation of the sacroliliac joint. METHODS Twenty fresh and freeze cadaver pelvises were prepared with pelvic fracture model,compared with different internal fixation systems such as Galveston(More)