Yi-Zhe Wu

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The Stromal cell-derived factor-1 (SDF-1)/CXC chemokine receptor 4 (CXCR4) system is considered to be of great importance in diseases involving cardiogenesis and angiogenesis. The SDF-1α-RAC signaling pathway plays a pivotal role in a cell’s polarity and serves to activate cell morphology variation and to control the direction of migration. We aimed to(More)
OBJECTIVE To investigate acute recoil of bioabsorbable poly-L-lactic acid (PLLA) stent. BACKGROUND As newly developed coronary stent, bioabsorbable PLLA stent still encountered concern of acute stent recoil. METHODS Sixteen minipigs were enrolled in our study. Eight PLLA XINSORB stents (Weite Biotechnology Co., Ltd., China) and eight metallic stents(More)
BACKGROUND Renal sympathetic nerves are involved in the reflective activation of the sympathetic nervous system in circulatory control. Catheter-based renal denervation (RDN) ameliorated treatment-resistant hypertension safely, but 10%-20% of treated patients are nonresponders to radiofrequency denervation. The purpose of this study was to investigate the(More)
Correspondence To the Editor: A 35‑year‑old man who smoked for 15 years suffered from chest pain 12 days ago before admission. He was diagnosed as myocardial infarction. Thrombolytic therapy was given consequently. The electrocardiogram showed sub‑acute inferior wall myocardial infarction. Echocardiogram showed attenuated constriction of the inferior wall(More)
BACKGROUND Despite great reduction of in-stent restenosis, first-generation drug-eluting stents (DESs) have increased the risk of late stent thrombosis due to delayed endothelialization. Arsenic trioxide, a natural substance that could inhibit cell proliferation and induce cell apoptosis, seems to be a promising surrogate of sirolimus to improve DES(More)
By combination of the structural features of flavones and isoflavones, a series of 3-benzylideneflavanone derivatives 12a–m with promising ClogP value were designed, synthesized and evaluated for their in vitro cytotoxic activities against four human tumor cell lines. Compound 12b exhibited the most potent activity (IC50 value against HL60, A549, HCT116 and(More)
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