Yi Xiaoli

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In this work we explored whether DNA methyltransferase 3a (Dnmt3a) targeted to the HBV X promoter (XP) causes epigenetic suppression of hepatitis B virus (HBV). The C-terminus of Dnmt3a (Dnmt3aC) was fused to a six-zinc-finger peptide specific to XP to form a fused DNA methyltransferase (XPDnmt3aC). The binding and methyl-modifying specificity of XPDnmt3aC(More)
This paper presents findings from usability evaluation of 'mPAL-my cpf' - a mobile government service provided by Central Provident Fund, Singapore. 20 users between 22-45 years of age participated in the tests. The focus of evaluation was to assess the mental model, information architecture and perceived utility of the overall application as well as(More)
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