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Increasing evidence shows that exercise training is neuroprotective after stroke, but the underlying mechanisms are unknown. To clarify this critical issue, the current study investigated the effects of early treadmill exercise on the expression of mitochondrial biogenesis factors. Adult rats were subjected to ischemia induced by middle cerebral artery(More)
A continuous flow left ventricle assist device (LVAD), which is mainly composed of a continuous flow blood pump and a physiological controller, has only one control input, the rotational speed of the pump, but at least three performance criteria to meet. The challenge for the physiological controller of a long-term continuous flow LVAD is the adaptability(More)
Neurogenesis is a complex process, which contributes to the ability of the adult brain to function normally and adapt to diseases. Epidermal growth factor (EGF) is known to play an important role in neurogenesis; however, the underlying mechanism is still unclear. Here, we hypothesized that brain-derived neurotrophic factor (BDNF) can enhance the effect of(More)
OBJECTIVE The development of obesity-related metabolic disorders varies with ethnicity. We examined whether ethnicity modifies the relationship between BMI and three metabolic pathways (insulin resistance, inflammation, and adiponectin) that are involved in the pathogenesis of diabetes and cardiovascular disease (CVD). RESEARCH DESIGN AND METHODS We(More)
In this paper, a state space model is developed through theoretical analysis and numerical solutions to approximate the response of human cardiovascular circulatory system. This system model has one critical time-varying parameter, the resistance of peripheral blood vessels. An parameter estimation scheme is derived to estimate this parameter, and the(More)
PRIMARY OBJECTIVE This study was designed to determine whether electro-acupuncture (EA) could alleviate cerebral oedema after cerebral ischemia. RESEARCH DESIGN EA has been widely used for cerebrovascular disease in East Asian countries. However, whether EA might reduce cerebral oedema after stroke remains unclear. In the current study, diffusion-weighted(More)
In practical application, the statistical characteristics of signal and noise are usually unknown or can't have been learned so that we hardly design fix coefficient digital filter. In allusion to this problem, the theory of the adaptive filter and adaptive noise cancellation are researched deeply in the thesis. According to the LMS and the RLS algorithms(More)
BACKGROUND Chinese medical universities typically have a high number of students, a shortage of teachers and limited equipment, and as such histology courses have been taught using traditional lecture-based formats, with textbooks and conventional microscopy. This method, however, has reduced creativity and problem-solving skills training in the curriculum.(More)
Stochastic computation is an unconventional computational paradigm that uses ordinary digital circuits to operate on stochastic bit streams, where signal value is encoded as the probability of ones in a stream. It is highly tolerant of soft errors and enables complex arithmetic operations to be implemented with simple circuitry. Prior research has proposed(More)