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Cullin-RING ligases (CRLs) represent the largest E3 ubiquitin ligase family in eukaryotes, and the identification of their substrates is critical to understanding regulation of the proteome. Using genetic and pharmacologic Cullin inactivation coupled with genetic (GPS) and proteomic (QUAINT) assays, we have identified hundreds of proteins whose stabilities(More)
In this paper we put our attention on gaining a set of effective acoustic model bestowed in an embedded phoneme-base mandarin name dialing system. Different sets of sub-word units are tested in the diverse vocabulary lists. The emission probability varied with the amount of mixtures and the type of covariance matrices is adopted. The speech feature with(More)
Glycosyl hydrolase family 16 (GHF16) truncated Fibrobacter succinogenes (TFs) and GHF17 barley 1,3-1,4-beta-D-glucanases (beta-glucanases) possess different structural folds, beta-jellyroll and (beta/alpha)8, although they both catalyze the specific hydrolysis of beta-1,4 glycosidic bonds adjacent to beta-1,3 linkages in mixed beta-1,3 and beta-1,4(More)
—Cloud security becomes an important topic in recent years, as to overcome the botnet in a virtualized environment is a critical task for the cloud providers. Although numerous intrusion detection systems are available, yet it is not practical to install IDS in every virtual machine. In this paper, we argue that a virtual machine monitor (VMM) can support(More)
The discovery of novel antiviral materials is important because many infectious diseases are caused by viruses. Silver nanoparticles have demonstrated strong antiviral activity, and graphene is a potential antimicrobial material due to its large surface area, high carrier mobility, and biocompatibility. No studies on the antiviral activity of nanomaterials(More)
A simple chemical method was developed for preparing high valence silver (Ag)-loaded mesoporous silica (Ag-ethylenediaminetetraacetic acid (EDTA)-SBA-15), which showed strong antibacterial activity. Ag-EDTA-SBA-15 exhibited stronger and more effective antibacterial activity than commercial Ag nanoparticles did, and it offered high stability of high valence(More)
Turkey flocks have experienced turkey coronaviral enteritis sporadically in the United States since the 1990s. Twenty-four field isolates of turkey coronavirus (TCoV) from multiple states in the United States were recovered from 1994 to 2010 to determine the genetic relationships among them. The entire spike (S) gene of each TCoV isolate was amplified and(More)
We propose a detection mechanism that takes the advantage of virtualized environment and combines both passive and active detection approaches for detecting bot malware. Our proposed passive detection agent lies in the virtual machine monitor to profile the bot behavior and check against it with other hosts. The proposed active detection agent that performs(More)