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  • Jeffrey L. Staudinger, Bonnie Goodwin, +10 authors Steven Anthony Kliewer
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 2001 (First Publication: 13 March 2001)
  • The pregnane X receptor (PXR) is the molecular target for catatoxic steroids such as pregnenolone 16α-carbonitrile (PCN), which induce cytochrome P450 3A (CYP3A) expression and protect the body fromExpand