• Publications
  • Influence
Low Micromolar Zinc Accelerates the Fibrillization of Human Tau via Bridging of Cys-291 and Cys-322*
A hallmark of a group of neurodegenerative diseases such as Alzheimer disease is the formation of neurofibrillary tangles, which are principally composed of bundles of filaments formed byExpand
  • 133
  • 8
Intervention of electroacupuncture on spinal p38 MAPK/ATF-2/VR-1 pathway in treating inflammatory pain induced by CFA in rats
BackgroundPrevious studies have demonstrated that p38 MAPK signal transduction pathway plays an important role in the development and maintenance of inflammatory pain. Electroacupuncture (EA) canExpand
  • 57
  • 5
The tumor rejection effect of protein components from medicinal fungus
Abstract Medicinal fungi are renowned for their antitumor activity and have been used in oriental countries for thousands of years. Modern medicine has documented that polysaccharides are the mainExpand
  • 19
  • 5
Crowded Cell-like Environment Accelerates the Nucleation Step of Amyloidogenic Protein Misfolding*
To understand the role of a crowded physiological environment in the pathogenesis of neurodegenerative diseases, we report the following. 1) The formation of fibrous aggregates of the human TauExpand
  • 88
  • 4
Molecular mapping of the Pi2/9 allelic gene Pi2-2 conferring broad-spectrum resistance to Magnaporthe oryzae in the rice cultivar Jefferson
BackgroundUtilization of broad-spectrum resistance (R) genes is an effective and economical strategy to control the fungal pathogen Magnaporthe oryzae, the causal agent of the rice blast disease.Expand
  • 31
  • 2
  • PDF
Summer Temperature Variations since 1676 AD in Luya Mountain,Shanxi Province of China,Inferred from Tree Rings
A tree-ring chronology of 328 years is obtained by using the Regional Curve Standardization method based on conifer samples(Pinus tabulaeformis) collected from Luya Mountain,ShanxiExpand
  • 11
  • 2
Pathological hydrogen peroxide triggers the fibrillization of wild-type SOD1 via sulfenic acid modification of Cys-111
Amyotrophic lateral sclerosis (ALS) involves the abnormal posttranslational modifications and fibrillization of copper, zinc superoxide dismutase (SOD1) and TDP-43. However, how SOD1-catalyzedExpand
  • 20
  • 1
Electroacupuncture attenuates spinal nerve ligation-induced microglial activation mediated by p38 mitogen-activated protein kinase
ObjectiveTo investigate whether analgesic effect of electroacupuncture (EA) is affected by p38 mitogen-activated protein kinase (p38 MAPK) on microglia.MethodsThere were two experiments. TheExpand
  • 15
  • 1
Dysfunction of MiR-148a-NRP1 Functional Axis Suppresses Osteogenic Differentiation of Periodontal Ligament Stem Cells Under Inflammatory Microenvironment.
Periodontitis is a chronic inflammatory disease that can lead to the loss of periodontal bone tissue. The osteogenic potential of periodontal ligament stem cells (PDLSCs) is significantly decreasedExpand
  • 1
  • 1