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Revelation of p53-independent Function of MTA1 in DNA Damage Response via Modulation of the p21WAF1-Proliferating Cell Nuclear Antigen Pathway*
Although metastasis-associated protein 1 (MTA1), a component of the nucleosome remodeling and deacetylase (NuRD) complex, is a DNA-damage response protein and regulates p53-dependent DNA repair, itExpand
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Genomic Profiling Reveals the Potential Role of TCL1A and MDR1 Deficiency in Chemotherapy-Induced Cardiotoxicity
Background: Anthracyclines, such as doxorubicin (Adriamycin), are highly effective chemotherapeutic agents, but are well known to cause myocardial dysfunction and life-threatening congestive heartExpand
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BP1 Homeoprotein Enhances Metastatic Potential in ER-negative Breast Cancer
Tumor invasion and metastasis remain a major cause of mortality in breast cancer patients. It was reported that BP1, a homeobox isoform of DLX4, is overexpressed in 80% of breast cancer patients andExpand
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Aspirin insensitive thrombophilia: transcript profiling of blood identifies platelet abnormalities and HLA restriction.
Aspirin is the most widely used antiplatelet agent because it is safe, efficient, and inexpensive. However, a significant subset of patients does not exhibit a full inhibition of plateletExpand
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Genome-wide Analysis of BP1 Transcriptional Targets in Breast Cancer Cell Line Hs578T
Homeobox genes are known to be critically important in tumor development and progression. The BP1 (Beta Protein 1) gene, an isoform of DLX4, belongs to the Distal-less (DLX) subfamily of homeoboxExpand
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Generalizable Meta-Heuristic based on Temporal Estimation of Rewards for Large Scale Blackbox Optimization
TLDR
The generalization abilities of heuristic optimizers may deteriorate with the increment of the search space dimensionality. Expand
隔膜和熔融碳酸盐燃料电池 (MCFCS)性能的研究(英文)
作者联系地址:中国科学院大连化学物理研究所!辽宁大连116023,中国科学院大连化学物理研究所!辽宁大连116023,中国科学院大连化学物理研究所!辽宁大连116023,中国科学院大连化学物理研究所!辽宁大连116023,中国科学院大连化学物理研究所!辽宁大连116023,中国科学院大连化学物理研究所!辽宁大
BP1 Regulates PI3K/Akt Pathway by Targeting Vascular Endothelial Growth Factor (VEGF) in Breast Cancer
The progression of breast cancer has been linked to a splice variant of DLX4 homeobox transcription factor called BP1, which is overexpressed in 81% of primary breast cancer. Our ChIP-on-chip andExpand
Abstract 3910: DLX4 homeprotein enhances the invasiveness of Hs578T ER-negative breast cancer cells
Tumor invasion and metastasis remain a major cause of mortality in breast cancer patients. It was reported that BP1, a homeobox isoform of DLX4, is overexpressed in 80% of breast cancer patients andExpand