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PURPOSE Variants in the complement factor H (CFH) gene have been shown to be strongly associated with age-related macular degeneration (AMD). In this study, sequence alterations in CFH were investigated in 163 Chinese patients with exudative AMD and 155 unrelated Chinese control subjects. METHODS All the 22 CFH exons, intron-exon boundaries, and promoter(More)
Neuroblastoma is one of the most common malignant neoplasms in childhood. The most common clinical presentation of this tumour is abdominal mass. However, affected children may have various clinical presentations as a result of disseminated metastatic disease or associated paraneoplastic syndromes at the time of diagnosis. In this article we have outlined(More)
Managing iris prolapse After reading the article by Tint et al., we would like to share some comments and tips about dealing with iris prolapse. First, one principle we obey in iris prolapse is to maintain the anterior chamber pressure at a stable and relatively low level. The goal is to prevent recurrent prolapse and minimize damage to the iris, since we(More)
Factors affecting stromal hydration of clear corneal incision architecture We have some comments about the article by Calladine et al. thatwewould like to sharewith the authors. First, one factor thatmight cause the difference in architecture betweenhydrated clear corneal incisions (CCIs) and nonhydrated CCIs is the corneal stromal edema at the incision(More)
Th1-response plays a crucial role in determining pathogenesis of organ-specific autoimmune diseases. It is believed that both IL-12 and INF-alpha are initiators to regulate Th1-response. In our experimental autoimmune uveitis (EAU) model, both Lewis and Fischer 344 rats share the same MHC class II molecules, while Lewis rat is EAU susceptible and Fischer(More)
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