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We have introduced a G-quadruplex-binding ligand, 3,6-bis(1-methyl-4-vinylpyridinium)carbazole diiodide (BMVC), to verify the major structure of d(T2AG3)4 (H24) in potassium solution and examine the structural conversion of H24 in sodium solution upon potassium titration. The studies of circular dichroism, induced circular dichroism, spectral titration and(More)
Background: Standardized Dermatophagoides dust mite extracts are produced in the US from purified whole bodies. Growth media and the processes for separating mites from media vary among manufacturers. The FDA requires that mite extracts are standardized and labeled in AU/mL. Potency is determined using a laboratory ELISA competition method to compare the(More)
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