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The role of human placental multipotent mesenchymal stromal cells (hPMSCs) in placental inflammation is unknown. We hypothesize that hPMSCs are involved in the early phases of placental infection. hPMSCs were isolated from term placentas and neutrophils from peripheral blood. The expression of toll-like receptors (TLRs) and cytokines by hPMSCs was(More)
BACKGROUND Human placental mesenchymal stem cells (hPMCs) are thought to be multipotent, but their fate after in utero transplantation is not known. METHODS hPMCs isolated from term placenta were assessed for their phenotype markers, mutilineage capacity, and immunomodulatory properties. Their engraftment potential was analyzed in a pregnant rat model(More)
Human placental multipotent mesenchymal stromal cells (hPMSCs) can be isolated from term placenta, but their angiogenic ability and the regulatory pathways involved are not known. hPMSCs were shown to express integrins av, a4, a5, b1, b3, and b5 and could be induced to differentiate into cells expressing endothelial markers. Increases in cell surface(More)
We propose an in-place search algorithm for computing the exact solutions to the resource constrained scheduling problem. This algorithm supports operation chaining, pipelining and multicycling in the underlying scheduling problem. Based on two lower-bound estimation mechanisms that are capable of predicting the criterion values of search nodes represented(More)
The aim of this work was to investigate whether the oral bioavailability and brain regional distribution of (+)-catechin could be improved by utilizing elastic liposomes. Liposomes containing soy phosphatidylcholine, cholesterol, and Tween 80 in the presence of 15% ethanol were prepared by a thin-film method and subsequent sonication and extrusion. The(More)
Maternal cells can become engrafted in various fetal organs during pregnancy. The nature of the cells and the mechanisms of maternofetal cell trafficking are not clear. We demonstrate that human lineage-negative, CD34-negative (Lin(-)CD34(-)) multipotent mesenchymal stromal cells express alpha(2), alpha(4), alpha(5), and beta(1) integrins, which mediate(More)
Reactive oxygen species may cause oxidative damage in the placenta, yet some mechanisms must exist to reduce or prevent such damage. We investigated whether oxidative injury to placental endothelial cells is inhibited by activation of antioxidant enzymes by paracrine factors secreted by human placental multipotent mesenchymal stromal cells (hPMSC).(More)
Human placental multipotent mesenchymal stromal cells (hPMSCs) can be isolated from term placenta, but their angiogenic ability and the regulatory pathways involved are not known. hPMSCs were shown to express integrins alpha(v), alpha(4), alpha(5), beta(1), beta(3), and beta(5) and could be induced to differentiate into cells expressing endothelial markers.(More)
Scheduling is considered the most important task in a high-level synthesis process. A heuristic algorithm based on the A search to find optimal schedules quickly is presented. This algorithm reduces the computational effort required to obtain the best schedules on a pre-defined datapath by effectively pruning the non-promising search space. The pruning(More)
This paper describes an approach for using an ontological structure to analyze Yami ika-emotion phrases. The study of the emotion phrases of the Austronesian language is still in a very early stage. In this study, we designed an approach of using an ontology to simulate the previous study on emotion and cognition of another Philippine language. Based on the(More)