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- Publications
- Influence
Synthesis of chalcone derivatives as potential anti-diabetic agents.
- Chi-Ting Hsieh, Tusty-Jiuan Hsieh, +6 authors F. Chang
- Chemistry, Medicine
- Bioorganic & medicinal chemistry letters
- 15 June 2012
Chalcones bearing electron donating or electron withdrawing substitutions were prepared and their glucose uptake activity was evaluated. Chalcone derivatives were synthesized in one step protocol… Expand
6-Paradol and 6-Shogaol, the Pungent Compounds of Ginger, Promote Glucose Utilization in Adipocytes and Myotubes, and 6-Paradol Reduces Blood Glucose in High-Fat Diet-Fed Mice
- Chien-Kei Wei, Yi-Hong Tsai, +6 authors Fang-Rong Chang
- Medicine
- International journal of molecular sciences
- 1 January 2017
The anti-diabetic activity of ginger powder (Zingiber officinale) has been recently promoted, with the recommendation to be included as one of the dietary supplements for diabetic patients. However,… Expand
Melamine induces human renal proximal tubular cell injury via transforming growth factor-β and oxidative stress.
- T. Hsieh, Pei-Chen Hsieh, +4 authors M. Wu
- Chemistry, Medicine
- Toxicological sciences : an official journal of…
- 1 November 2012
Although several reports have failed to observe adverse subchronic renal effects following relatively high melamine exposure, the safety of low and continuous melamine exposure is still debatable.… Expand
Anti-diabetic properties of non-polar Toona sinensis Roem extract prepared by supercritical-CO2 fluid.
- T. Hsieh, Yi-Hong Tsai, +5 authors Y. Wu
- Chemistry, Medicine
- Food and chemical toxicology : an international…
- 1 March 2012
Toona sinensis Roem (T. sinensis) leaves have been used as a nutritious vegetable and been suggested for medical applications; however, the reported bioactive compounds of T. sinensis leaves are, so… Expand
Anti-neutrophilic inflammatory steroidal glycosides from Solanum torvum.
Torvpregnanosides A and B, two pregnane glycosides, and torvoside Q, a 23-keto-spirostanol glycoside, along with twelve known steroidal saponins were isolated from aerial parts of Solanum torvum. Of… Expand
Anti-allergic Hydroxy Fatty Acids from Typhonium blumei Explored through ChemGPS-NP
- M. Korinek, Yi-Hong Tsai, +11 authors Fang-Rong Chang
- Chemistry, Medicine
- Front. Pharmacol.
- 19 June 2017
Increasing prevalence of allergic diseases with an inadequate variety of treatment drives forward search for new alternative drugs. Fatty acids, abundant in nature, are regarded as important… Expand