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Lipid droplets (LDs) are cellular storage organelles for neutral lipids that vary in size and abundance according to cellular needs. Physiological conditions that promote lipid storage rapidly and markedly increase LD volume and surface. How the need for surface phospholipids is sensed and balanced during this process is unknown. Here, we show that(More)
Eukaryotic cells store neutral lipids in cytoplasmic lipid droplets enclosed in a monolayer of phospholipids and associated proteins. These dynamic organelles serve as the principal reservoirs for storing cellular energy and for the building blocks for membrane lipids. Excessive lipid accumulation in cells is a central feature of obesity, diabetes and(More)
This poster introduces SLAW, a Scalable Locality-aware Adaptive Work-stealing scheduler. The SLAW features an adaptive task scheduling algorithm combined with a locality-aware scheduling framework. Past work has demonstrated the pros and cons of using fixed scheduling policies, such as <i>work-first</i> and <i>help-first</i>, in different cases without a(More)
Colon cancer has been viewed as the result of progressive accumulation of genetic and epigenetic abnormalities. However, this view does not fully reflect the molecular heterogeneity of the disease. We have analyzed both genetic (mutations of BRAF, KRAS, and p53 and microsatellite instability) and epigenetic alterations (DNA methylation of 27 CpG island(More)
The apoplast of plant cells, which carries out multiple functions in plant metabolism and signaling, is not only a barrier but also the linker between the environment and the protoplast. To investigate the role of apoplastic proteins in the salt stress response, 10-d-old rice (Oryza sativa) plants were treated with 200 mM NaCl for 1, 3, or 6 h, and the(More)
for the "nancial support during his stay in Sydney University for his sabbatical leave in 1998. Abstract This paper describes an application of nonlinear decentralized robust control (Guo, Jiang & Hill, 1998) to large-scale power systems. Decentralized power controllers are designed explicitly to maintain transient stable closed-loop systems. For the "rst(More)
Multiple programming models are emerging to address an increased need for dynamic task parallelism in multicore shared-memory multiprocessors. This poster describes the main components of Rice University's Habanero Multicore Software Research Project, which proposes a new approach to multicore software enablement based on a two-level programming model(More)
RFID technology has been widely adopted in a variety of applications from logistics to access control. Many applications gain benefits from knowing the exact position of an RFID-tagged object. Existing localization algorithms in wireless network, however, can hardly be directly employed due to tag's limited capabilities in terms of energy and memory. For(More)
BACKGROUND Lipid droplets are ubiquitous organelles that are among the basic building blocks of eukaryotic cells. Despite central roles for cholesterol homeostasis and lipid metabolism, their function and protein composition are poorly understood. RESULTS We purified lipid droplets from Drosophila embryos and analyzed the associated proteins by capillary(More)
OBJECTIVE To report the performance of massively parallel sequencing (MPS) based prenatal noninvasive fetal trisomy test based on cell-free DNA sequencing from maternal plasma in a routine clinical setting in China. METHOD The MPS-based test was offered as a prenatal screening test for trisomies 21 and 18 to pregnant women in 49 medical centers over 2(More)