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BACKGROUND Difficulty attending is a common deficit of schizophrenic patients. However, it is not known whether this is a global attentional deficit or relates to a specific attentional network. METHOD This study used the attention network test to compare schizophrenic patients (N=77) with controls (N=53) on the efficiency of three anatomically defined(More)
This paper studied the effect of neurosteroid dehydroepiandrosterone sulfate on spontaneous glutamate release in the prelimbic cortex by using electrophysiological and biochemical methods combined with a pharmacological approach and made some comparisons with those in the hippocampus. The results showed that dehydroepiandrosterone sulfate increased the(More)
One approach to conveying tactile feedback from sensorized neural prostheses is to characterize the neural signals that would normally be produced in an intact limb and reproduce them through electrical stimulation of the residual peripheral nerves. Toward this end, we have developed an integrate-and-fire model that predicts with millisecond accuracy the(More)
—In this letter, we proposed an asymmetrical interfer-ometer to compensate the pattern effect in semiconductor optical amplifier (SOA) as an inline amplifier in dense wavelength-division -multiplexing (DWDM) system. In this letter, experiments are demonstrated with a commercial integrated Mach–Zehnder inter-ferometer (MZI)-SOA. The experiments showed that(More)
Visual attention is often understood as a modulatory field acting at early stages of processing, but the mechanisms that direct and fit the field to the attended object are not known. We show that a purely spatial attention field propagating downward in the neuronal network responsible for perceptual organization will be reshaped, repositioned, and(More)
We tested the binding-by-synchrony hypothesis which proposes that object representations are formed by synchronizing spike activity between neurons that code features of the same object. We studied responses of 32 pairs of neurons recorded with microelectrodes 3 mm apart in the visual cortex of macaques performing a fixation task. Upon mapping the receptive(More)
Wilson's disease (WD) is a hereditary disorder of copper metabolism resulting from mutations within ATP7B. Clinical investigations showed that ATP7B missense mutations cause a wide variety of symptoms in WD patients, which implies that those mutations might affect ATP7B function in a number of ways and each would have deleterious consequences on normal(More)
To study the roles of microRNA-223 (miR-223) in regulation of cell growth, we established a miR-223 over-expression model in HeLa cells infected with miR-223 by Lentivirus pLL3.7 system. We observed in this model that miR-223 significantly suppressed the proliferation, growth rate, colony formation of HeLa cells in vitro, and in vivo tumorigenicity or tumor(More)
AIMS Wilson's disease is an autosomal recessive disorder of copper metabolism due to mutations within ATP7B gene. Clinical investigations indicate that ATP7B truncations are associated with an early age of onset when compared to its missense mutations. In vitro studies show that mislocalization of ATP7B mutants is involved in disease-causing mechanisms.(More)