Yi-Chun Wang

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BACKGROUND The insulin-like growth factor (IGF) axis is an important signaling pathway in the growth and survival of many cell and tissue types. This pathway has also been implicated in many aspects of cancer progression from tumorigenesis to metastasis. The multiple roles of IGF signaling in cancer suggest that inhibition of the pathway might yield(More)
BACKGROUND It is well known that the quality of life of patients with chronic kidney disease can be improved by dialysis. While previous studies have used retrospective designs and adhered to a standard target prescribed by clinical guidelines, our study prospectively investigates the association between the adequacy of peritoneal dialysis (PD) and measures(More)
It has been proposed that pericentromeric satellite DNA arises from the progressive proximal expansion of ancient centromeric DNA. In an attempt to recover putative ancestral centromeric DNA, we microdissected the pericentromeric/centromeric DNA from the chromosome X + 3 of Indian muntjac (Muntiacus muntjak vaginalis) and constructed a microclone-library of(More)
Two Hamiltonian cycles $$C_1=\langle u_0,u_1,u_2,...,u_{n-1},u_0 \rangle $$ C 1 = ⟨ u 0 , u 1 , u 2 , . . . , u n - 1 , u 0 ⟩ and $$C_2=\langle v_0,v_1,v_2,...,v_{n-1},v_0 \rangle $$ C 2 = ⟨ v 0 , v 1 , v 2 , . . . , v n - 1 , v 0 ⟩ of a graph G are independent starting at $$u_0$$ u 0 if $$u_0=v_0, u_i\ne v_i$$ u 0 = v 0 , u i ≠ v i for all $$1\le i\le(More)
Highly conserved sequences (regions or domains) play an important role in phylogenetic analysis. In this study, a novel approach to extract highly conserved sequences as representative regions for the genuses of viruses via protein sequences clustering is proposed. A representative region of one genus is extracted from one distinctive protein sequence group(More)