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Understanding another person's experience draws on "mirroring systems," brain circuitries shared by the subject's own actions/feelings and by similar states observed in others. Lately, also the experience of pain has been shown to activate partly the same brain areas in the subjects' own and in the observer's brain. Recent studies show remarkable overlap(More)
In the absence of external stimuli, human hemodynamic brain activity displays slow intrinsic variations. To find out whether such fluctuations would be altered by persistent pain, we asked 10 patients with unrelenting chronic pain of different etiologies and 10 sex- and age-matched control subjects to rest with eyes open during 3-T functional MRI.(More)
In search for suitable tools to study brain activation in natural environments, where the stimuli are multimodal, poorly predictable and irregularly varying, we collected functional magnetic resonance imaging data from 6 subjects during a continuous 8-min stimulus sequence that comprised auditory (speech or tone pips), visual (video clips dominated by(More)
Vibrotactile stimuli can facilitate hearing, both in hearing-impaired and in normally hearing people. Accordingly, the sounds of hands exploring a surface contribute to the explorer's haptic percepts. As a possible brain basis of such phenomena, functional brain imaging has identified activations specific to audiotactile interaction in secondary(More)
The whole human primary somatosensory (SI) cortex is activated by contralateral tactile stimuli, whereas its subarea 2 displays neuronal responses also to ipsilateral stimuli. Here we report on a transient deactivation of area 3b of the ipsilateral SI during long-lasting tactile stimulation. We collected functional magnetic resonance imaging data with a 3 T(More)
In models of letter recognition, handwritten letters are considered as a particular font exemplar, not qualitatively different in their processing from printed letters. Yet, some data suggest that recognizing handwritten letters might rely on distinct processes, possibly related to motor knowledge. We applied functional magnetic resonance imaging to compare(More)
Independent component analysis (ICA) can unravel functional brain networks from functional magnetic resonance imaging (fMRI) data. The number of the estimated components affects both the spatial pattern of the identified networks and their time-course estimates. Here group-ICA was applied at four dimensionalities (10, 20, 40, and 58 components) to fMRI data(More)
When decomposing single trial electroencephalography it is a challenge to incorporate prior physiological knowledge. Here, we develop a method that uses prior information about the phase-locking property of event-related potentials in a regularization framework to bias a blind source separation algorithm toward an improved separation of single-trial(More)
A recent study described for the first time a patient group that suffered from spontaneous chronic pain and from recurrent herpes simplex virus (HSV) infections. The patients had pain in widespread areas on one side of the body and were--due to subtle immunological abnormalities--susceptible to HSV infections. Although the clinical features of the pain(More)
Competition imposes constraints for humans who make decisions. Concomitantly, people do not only maximize their personal profit but they also try to punish unfair conspecifics. In bargaining games, subjects typically accept equal-share offers but reject unduly small offers; competition affects this balance. Here we used functional magnetic resonance imaging(More)