Yen-Ming Hsu

Timothy Bourne1
Jixin Ding1
David Hutto1
1Timothy Bourne
1Jixin Ding
1David Hutto
Learn More
  • Sara Maia, Marc Pelletier, Jixin Ding, Yen-Ming Hsu, Stephen E. Sallan, Sambasiva P. Rao +2 others
  • 2011
Despite exhibiting oncogenic events, patient's leukemia cells are responsive and dependent on signals from their malignant bone marrow (BM) microenvironment, which modulate their survival, cell cycle progression, trafficking and resistance to chemotherapy. Identification of the signaling pathways mediating this leukemia/microenvironment interplay is(More)
INTRODUCTION CD40 ligand (CD40L) blockade has demonstrated efficacy in experimental autoimmune models. However, clinical trials of hu5c8, an anti-human CD40L IgG1 antibody, in systemic lupus erythematosus (SLE) were halted due to an increased incidence of thrombotic events. This study evaluated CDP7657, a high affinity PEGylated monovalent Fab' anti-CD40L(More)
  • 1