Yen-Kung Chen

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PURPOSE The purpose of this study was to further localize cerebral perfusion abnormalities, and to better correlate these abnormalities with the clinical severity of Parkinson's disease (PD). METHODS A single-photon emission computed tomography (SPECT) study was performed on 27 patients with PD and 24 age-matched controls. SPECT images were spatially(More)
UNLABELLED Focally increased (18)F-FDG uptake in the lateral pharyngeal recess (LPR) of the nasopharynx due to a benign or malignant lesion is not an uncommon finding on PET images. The aim of this study was to evaluate whether, on PET/CT images, (18)F-FDG uptake occurs with characteristic patterns and intensities in various regions of Waldeyer's ring that(More)
OBJECTIVE To determine the risk of osteoporosis in patients with myasthenia gravis (MG) in a large cohort representing 99% of the population of Taiwan. METHODS Data from the Taiwan National Health Insurance Research Database were used to conduct retrospective cohort analyses. The study cohort consisted of 2,073 patients with MG who were 3-fold(More)
Hypoperfusion on single-photon emission computed tomography (SPECT) of the stroke-like lesion (SLL) at the hyperacute stage of mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS) is considered to be a supportive evidence of the mitochondrial angiopathy theory. Our objectives were to examine whether other neuroimages,(More)
The aim of this study was to determine the risk of myasthenia gravis (MG) in patients with allergic or autoimmune thyroid disease in a large cohort representing 99% of the population in Taiwan. Data from the Taiwan National Health Insurance Database were used to conduct retrospective analyses. The study comprised 1689 adult patients with MG who were 4-fold(More)
The exact relationship between myasthenia gravis (MG) and extrathymic malignancies has not been established thus far. Occasional cases of MG have been reported in association with lymphoma or other lymphoproliferative disorders. To determine the risk of extrathymic malignancy with particular attention on lymphoid malignancy for MG patients in a large cohort(More)
Background: Coronary fistula is a congenital anomaly resulting in steal phenomenon of coronary blood flow, which may result in clinical symptoms and/or signs of coronary artery disease (CAD), including angina pec-toris, myocardial ischemia, and congestive heart failure. The purpose of this study is to do a retrospective analysis of myocardial ischemia in(More)
A 57-year-old female underwent whole-body 18 F-fluo-rodeoxyglucose positron emission tomography (FDG-PET) study for health examination. There is increased FDG uptake in the left scapula, the left side ribs and bilateral femora. Fibrous dysplasia, sexual precocity and hyperthroidism history was then told. She also received thyroidectomy and 131 I radioiodine(More)
RATIONALE According to the metabolic symbiosis model, cancer stromal fibroblasts could be hijacked by surrounding cancer cells into a state of autophagy with aerobic glycolysis to help provide recycled nutrients. The purpose of this study was to investigate whether combined treatment with the autophagy inhibitor: hydroxychloroquine (HCQ) and the autophagy(More)
Breast cancer is the most common cancer in females. The liver is the third most common site for breast cancer to spread to after bone and lung. On the other hand, the primary hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. The conventional tools to evaluate primary HCC and liver metastases include liver blood tests, abdominal US,(More)