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The pattern languages are languages that are generated from patterns, and were first proposed by Angluin as a non-trivial class that is inferable from positive data [D. Angluin, Finding patterns common to a set of strings, Journal of Computer and System Sciences 21 (1980) 46–62; D. Angluin, Inductive inference of formal languages from positive data,(More)
This study reports Müller cell and neuronal changes and microglial reaction in streptozotocin-induced diabetic rats. Glial fibrillary acidic protein (GFAP) immunoreactivity was largely confined to astrocytes in the nerve fiber layer (NFL) and ganglion cell layer (GCL) in control rats. In diabetic rats especially those killed after 12 months, GFAP(More)
Glaucoma is a common disease seen in the eye clinic, but its associated pathological processes, especially the role of glial cells in glaucomatous retinae, are still under debate. The aim of the present work was to study the responses of astrocytes, Müller cells and microglia in retinae of rats with experimental glaucoma. Glaucoma was induced in adult male(More)
The present study was initiated to investigate neuronal degeneration, microglial reactivity and possible roles of NO in the lateral geniculate nucleus (LGN) of glaucomatous rats. An experimental one-eye glaucoma model was created by cauterization of the limbal-derived veins. Neuronal cell viability was studied by immunostaining with antibody against(More)
The distribution of nitric oxide synthase-containing neurons was studied in the rat and mouse hypothalamus by immunohistochemistry and NADPH-diaphorase histochemistry. Immunostaining and NADPH-diaphorase staining of hypothalamic neurons were comparable in all hypothalamic nuclei of either species except in the arcuate nucleus that stained positive for(More)
Injection of a minute amount of the toxic lectin, Ricinus communis agglutinin-60 (RCA-60) into the vagus nerve resulted in a selective destruction of the vagal efferent neurons in the ipsilateral dorsal motor nucleus (DMN). This has elicited a massive influx of mononuclear leucocytes, notably macrophages and T-lymphocytes, as detected with ED-1 and OX-19(More)
In this paper we examine the issues involved in finding consensus patterns from biosequence data of very small sample sizes, by searching for so-called minimal multiple generalization (mmg), that is, a set of syntactically minimal patterns that accounts for all the samples. The data we use are the sigma regulons with more conserved consensus patterns for(More)
BACKGROUND Ab initio protein structure prediction methods generate numerous structural candidates, which are referred to as decoys. The decoy with the most number of neighbors of up to a threshold distance is typically identified as the most representative decoy. However, the clustering of decoys needed for this criterion involves computations with runtimes(More)
BACKGROUND Co-expressing genes tend to cluster in eukaryotic genomes. This paper analyzes correlation between the proximity of eukaryotic genes and their transcriptional expression pattern in the zebrafish (Danio rerio) genome using available microarray data and gene annotation. RESULTS The analyses show that neighbouring genes are significantly(More)