Yen-Hsiang Chang

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Brown adipose tissue (BAT) is important for regulating body weight. Environmental temperature influences BAT activation. Activated BAT is identifiable using (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT). (18)F-FDG PET/CT scans done between June 2005 and May 2009 in our institution in tropical southern Taiwan(More)
Amyloid load, as measured by florbetapir positron emission tomography (PET) standardized uptake value ratio (SUVr), has high specificity in the diagnosis of Alzheimer disease (AD). As the posterior cingulate cortex (PCC) represents densely amyloid-affected regions early in AD, we hypothesized that amyloid load within the key hubs of the default mode(More)
The aim of this study was to investigate the biomechanical interactions between cuspal preparation designs and cement thickness in a cusp-replacing ceramic premolar restoration. The cavity was designed in a typical MODP (mesial-occlusal-distal- palatal) restoration failure shape when the palatal cusp has been lost. Twelve 3D finite element (FE) models with(More)
OBJECTIVES The structural stability and adhesive strength of a large-cavity premolar with a CEREC restoration is a frequent problem in long-term use. This study sought to determine whether an additional reinforced slot could increase tooth/ceramic retention using finite element (FE) analysis and fracture testing. METHODS The cavity was designed in a(More)
OBJECTIVES This study investigates the biomechanical interactions among restorative materials, cuspal preparation designs, and cement thickness in a cusp-replacing adhesive premolar restoration. METHODS Twenty-seven, 3D finite element (FE) models designed in a typical MODL restoration with three restorative materials (CAD/CAM ceramic block, indirect resin(More)
OBJECTIVES The aim of this study was to determine the relative contribution of changes in restorative material, cavity dimensions, adhesive layer adaptation, and load conditions on the biomechanical response of an adhesive Class II MOD restoration during oral temperature changes. METHODS A validated finite-element (FE) model was used to perform the(More)
INTRODUCTION This study evaluated the risk of failure for an endodontically treated premolar with mesio occlusodistal palatal (MODP) preparation and 3 different computer-aided design/computer-aided manufacturing (CAD/CAM) ceramic restoration configurations. METHODS Three 3-dimensional finite element (FE) models designed with CAD/CAM ceramic onlay,(More)
OBJECTIVES This study determines the relative contribution of changes (design factors) in cavity dimension, restorative material, adhesive layer modulus and thickness and loading condition on the biomechanical response of a premolar adhesive Class II MOD restoration. METHODS A validated finite element (FE) model was used to simulate the mechanical(More)
OBJECTIVES This study evaluated the risk of failure for an endodontically treated premolar with MOD preparation and three CEREC ceramic restoration configurations. METHODS Simulations were performed based on three 3D finite element (FE) models designed with CEREC ceramic inlay, endocrown and conventional crown restorations. Long-term failure probability(More)
The present study evaluated the failure risks of an endodontically treated premolar with severely damaged coronal hard tissue and restored with either a computer-aided design/computer-aided manufacturing (CAD/CAM) ceramic endocrown or a classical crown configuration. Two, three-dimensional finite element maxillary premolar models were designed with(More)