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OBJECTIVES The structural stability and adhesive strength of a large-cavity premolar with a CEREC restoration is a frequent problem in long-term use. This study sought to determine whether an additional reinforced slot could increase tooth/ceramic retention using finite element (FE) analysis and fracture testing. METHODS The cavity was designed in a(More)
INTRODUCTION This study evaluated the risk of failure for an endodontically treated premolar with mesio occlusodistal palatal (MODP) preparation and 3 different computer-aided design/computer-aided manufacturing (CAD/CAM) ceramic restoration configurations. METHODS Three 3-dimensional finite element (FE) models designed with CAD/CAM ceramic onlay,(More)
OBJECTIVES This study evaluated the risk of failure for an endodontically treated premolar with MOD preparation and three CEREC ceramic restoration configurations. METHODS Simulations were performed based on three 3D finite element (FE) models designed with CEREC ceramic inlay, endocrown and conventional crown restorations. Long-term failure probability(More)
Amyloid load, as measured by florbetapir positron emission tomography (PET) standardized uptake value ratio (SUVr), has high specificity in the diagnosis of Alzheimer disease (AD). As the posterior cingulate cortex (PCC) represents densely amyloid-affected regions early in AD, we hypothesized that amyloid load within the key hubs of the default mode(More)
OBJECTIVES This study investigates the biomechanical interactions among restorative materials, cuspal preparation designs, and cement thickness in a cusp-replacing adhesive premolar restoration. METHODS Twenty-seven, 3D finite element (FE) models designed in a typical MODL restoration with three restorative materials (CAD/CAM ceramic block, indirect resin(More)
The aim of this study was to investigate the biomechanical interactions between cuspal preparation designs and cement thickness in a cusp-replacing ceramic premolar restoration. The cavity was designed in a typical MODP (mesial-occlusal-distal- palatal) restoration failure shape when the palatal cusp has been lost. Twelve 3D finite element (FE) models with(More)
OBJECTIVE This study investigates monitored micro-crack growth and damage in the ceramic/enamel adhesive interface using the acoustic emission (AE) technique with optical coherence tomography (OCT) under fatigue shear testing. METHODS Shear bond strength (SBS) was measured first with eight prepared ceramic/enamel adhesive specimens under static loads. The(More)
While carbon monoxide (CO) intoxication often triggers multiple intraneuronal immune- or inflammatory-related cascades, it is not known whether the pathological processes within the affected regions evolve equally in the long term. To understand the neurodegenerative networks, we examined 49 patients with a clinical diagnosis of CO intoxication related to(More)
INTRODUCTION This study evaluated the risk of failure for an endodontically treated premolar with different crack depths, which was shearing toward the pulp chamber and was restored by using 3 different computer-aided design/computer-aided manufacturing ceramic restoration configurations. METHODS Three 3-dimensional finite element models designed with(More)
OBJECTIVES The aim of this study was to determine the relative contribution of changes in restorative material, cavity dimensions, adhesive layer adaptation, and load conditions on the biomechanical response of an adhesive Class II MOD restoration during oral temperature changes. METHODS A validated finite-element (FE) model was used to perform the(More)