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  • Yehuda G. Assaraf
  • Medicine, Biology
  • Cancer and Metastasis Reviews
  • 2007 (First Publication: 20 March 2007)
  • Folates play a key role in one-carbon metabolism essential for the biosynthesis of purines, thymidylate and hence DNA replication. The antifolate methotrexate has been rationally-designed nearly 60Expand
  • Yehuda G. Assaraf, Lutfi Abu-Elheiga, Dan T. Spira, Hans Desser, Uriel Bachrach
  • Biology, Medicine
  • The Biochemical journal
  • 1987 (First Publication: 15 February 1987)
  • DL-alpha-Difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase, prevented the increases in putrescine and spermidine, but not in spermine, in human erythrocytesExpand