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BACKGROUND Streptococcus pneumoniae is a leading cause of hospitalization in HIV-infected adults therefore pneumococcal vaccine is recommended. The ideal antipneumococcal vaccine and effective vaccination regimen remain controversial and needs further evaluation. METHODS To assess the efficacy of pneumococcal vaccines alone and combined, a randomized,(More)
Since the first edition of Surviving Sepsis Campaign Guidelines, the administration of intravenous antibiotics in the first hours of sepsis is recommend. However, in the last ten years, several studies around importance of early antibiotics in emergency room or in intensive care unit produced disparate results. Therefore, is early administration of(More)
INTRODUCTION Population aging has become a global phenomenon, and HIV infection among older individuals is also increasing. Because age can affect the progression of HIV infection, we aimed to evaluate the present knowledge on HIV infection in older patients. METHODS Literature review of the last 20 years. RESULTS Older HIV-infected patients have lower(More)
We present a case of a 16-year-old male patient with sudden-onset, rash, arthritis and meningitis by Neisseria meningitidis one week after an acute upper respiratory infection. On the 10th day of treatment followed by neurological and arthritis clinical improvement, he presented once again a tender and swollen left knee with a moderate effusion, and active(More)
Once rare, septic shock (SS) due to disseminated fungal infections has been increasingly reported due to a growing number of immunocompromised patients, but remains rare in non-immune-compromised individuals. In paracoccidioidomycosis, it has been described in only three patients with the severe, acute form of the disease. We describe the development of a(More)
Tetanus is a treatable and preventable disease that remains prevalent in developing countries. The mortality rate can reach up to 30 %. The early mortality is due to acute respiratory failure secondary to muscle spasms. Given that the tracheal tube stimulates muscle spasms, there is worldwide consensus to perform early tracheostomy on tetanus patients who(More)
Dear Editor, After the 2009 influenza H1N1 pandemic, several reports have described acute kidney injury (AKI) in patients with influenza-A(H1N1)-2009 infection. Kidney injury was generally attributed to rhabdomyolysis or to haemodynamic instability [1–5]. We report an evidence of a possible direct action of influenza-A(H1N1)-2009 on kidney injury. On 22(More)
OBJECTIVE Despite the decline in the incidence of tetanus, this disease is still neglected in the developing world and remains a major cause of morbidity and mortality. With improvements in intensive care, it is important to better understand the complications of this serious condition. We aim to evaluate 1) the lethality and osteomuscular and(More)
Although tetanus can be prevented by appropriate immunization, accidental tetanus continues to occur frequently in underdeveloped and developing countries. Tetanus mortality rates remain high in these areas, and studies regarding the best therapy for tetanus are scarce. Because of the paucity of data on accidental tetanus and the clinical relevance of this(More)
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