Yee-Shuan Lee

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Neural tissue engineering may be a promising option for neural repair treatment, for which a well-designed scaffold is essential. Smart materials that can stimulate neurite extension and outgrowth have been investigated as potential scaffolding materials. A piezoelectric polymer polyvinylidene fluoride-trifluoroethylene (PVDF-TrFE) was used to fabricate(More)
A bibliometric analysis was performed to assess the quantitative trend of Patent Ductus Arteriosus (PDA) treatment research, including intravenous injection of indomethacin and surgery. The documents studied were retrieved from the Science Citation Index (SCI) for the period from 1991 to 2002. The publication pattern concerning authorship, collaboration,(More)
Human neural stem/progenitor cells (hNSCs/NPCs) are a promising cell source for neural tissue engineering because of their ability to differentiate into various neural lineages. In this study, hNSC/NPC differentiation was evaluated on piezoelectric, fibrous scaffolds. These smart materials have an intrinsic material property where transient electric(More)
Allograft (Allo) incorporation in the presence of a systemic disease like diabetes mellitus (DM) is becoming a major issue in the orthopedic community. Mesenchymal stem cells (MSC) are multipotent stem cells that may be derived from adult, whole bone marrow and have been shown to induce bone formation in segmental defects when combined with the appropriate(More)
Schwann cell (SC) transplantation has been utilized for spinal cord repair and demonstrated to be a promising therapeutic strategy. In this study, we investigated the feasibility of combining SC transplantation with novel conduits to bridge the completely transected adult rat spinal cord. This is the first and initial study to evaluate the potential of(More)
Statement of Purpose: Electric fields can influence neural growth and orientation in vitro (Patel NB. J Neurosci. 1984; 4:2939-47) and have been applied for the treatment of spinal cord injuries in recent clinical trials (Duffell LD. Mus Nerve. 2008; 38: 1304-11). Poly vinyldifluoride-trifluropolyethylene (PVDF-TrFE), a piezoelectric polymer, can induce a(More)
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