Yedla Poornachandra

Learn More
A series of new N-alkyl-2-(3-methyl-indolyl)benzimidazoles 8(a–c) were synthesized by the condensation of N-alkyl-2-propylbenzimidazole-phenylhydrazone derivatives 7(a–c), in polyphosphoric acid (PPA) underwent cyclization via Fischer-indole synthesis. Alkylation of 8(b–c) with different alkylating agents gave the title compounds 9(a–f). All the synthesized(More)
This study presents the synthesis of 14 new 1,4-disubstituted piperazine derivatives from allyl bromides of Baylis–Hillman adduct and 4,4-disubstituted benzhydryl piperazines. All the synthesized compounds were further screened for in vitro ACE inhibitor and antimicrobial activities. Among the synthesized piperazine derivatives, compound 12h showed moderate(More)
  • 1