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In this paper, we propose a new PDE-based methodology for deformable surfaces that is capable of automatically evolving its shape to capture the geometric boundary of the data and simultaneously discover its underlying topological structure. Our model can handle multiple types of data (such as volumetric data, 3D point clouds and 2D image data), using a(More)
We propose a semi-automatic thalamus and thalamus nuclei segmentation algorithm from Diffusion Tensor Magnetic Resonance Imaging (DT-MRI) based on the mean-shift algorithm. Comparing with existing thalamus segmentation algorithms which are mainly based on K-means algorithm, our mean-shift based algorithm is more flexible and adaptive. It does not assume a(More)
BACKGROUND The brain develops in concert and in coordination with the developing facial tissues, with each influencing the development of the other and sharing genetic signaling pathways. Autism spectrum disorders (ASDs) result from alterations in the embryological brain, suggesting that the development of the faces of children with ASD may result in subtle(More)
A new color photometric stereo method is presented, which reconstructs both albedo and shape from three color images. Optical polarization filters are placed in front of the light source and a camera to capture images free from specular reflection components. First, the albedo maps are derived from three color images. Then, the shape is reconstructed based(More)
The dystrophin-deficient dog is excellent large animal model for testing novel therapeutic modalities for Duchenne muscular dystrophy (DMD). Despite well-documented descriptions of dystrophic symptoms in these dogs, very few quantitative studies have been performed. Here, we developed a comprehensive set of non-invasive assays to quantify dog gait (stride(More)
We propose a new context-sensitive active contour for 2D corpus callosum segmentation. After a seed contour consisting of interconnected parts is being initialized by the user, each part will start to deform according to its own motion law derived from high-level prior knowledge, and is constantly aware of its own orientation and destination during the(More)
Traditional Chinese Medicine (TCM) has a long history and has been recognized as a popular alternative medicine in western countries. Tongue diagnosis is a significant procedure in computer-aided TCM, where tongue image analysis plays a dominant role. In this paper, we proposed a fully automatic tongue detection and tongue segmentation framework, which is(More)
Phenylketonuria (PKU) is a genetic disorder characterised by an inability to metabolise phenylalanine. Several studies have reported that the Corpus Callosum (CC) is one of the most severely affected structures with respect to volume loss in early treated PKU patients. In this work, we aim to detect the abnormalities of the CC in PKU from both global and(More)