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Megastore is a storage system developed to meet the requirements of today’s interactive online services. Megastore blends the scalability of a NoSQL datastore with the convenience of a traditional RDBMS in a novel way, and provides both strong consistency guarantees and high availability. We provide fully serializable ACID semantics within fine-grained(More)
The ADP-ribosylation factors (Arfs) are six proteins within the larger Arf family and Ras superfamily that regulate membrane traffic. Arfs all share numerous biochemical activities and have very similar specific activities. The use of dominant mutants and brefeldin A has been important to the discovery of the cellular functions of Arfs but lack specificity(More)
An HPLC-DAD method has been developed to quantitatively analyze for the content of zeaxanthin dipalmitate, a major carotenoid in Fructus Lycii, in different species of the genus Lycium. Determination was performed using an Alltima C18 column with the mobile phase consisting of acetonitrile and dichloromethane (42:58). The total contents of carotenoids in(More)
ADP-ribosylation factor (Arf) and Arf-like (Arl) proteins are a family of highly conserved 21 kDa GTPases that emerged early in the evolution of eukaryotes. These proteins serve regulatory roles in vesicular traffic, lipid metabolism, microtubule dynamics, development, and likely other cellular processes. We found evidence for the presence of 6 Arf family(More)
For some sensor network applications, the problem of sweep coverage, which periodically covers POIs (Points of Interest) to sense events, is of importance. How to schedule minimum number of mobile sensors to achieve the sweep coverage within specified sweep period is a challenging problem, especially when the POIs to be scanned exceeds certain scale and the(More)
Arl2 and Arl3 are closely related members of the Arf family of regulatory GTPases that arose from a common ancestor early in eukaryotic evolution yet retain extensive structural, biochemical, and functional features. The presence of Arl3 in centrosomes, mitotic spindles, midzones, midbodies, and cilia are all supportive of roles in microtubule-dependent(More)
Coat proteins cycle between soluble and membrane-bound locations at the time of vesicle biogenesis and act to regulate the assembly of the vesicle coat that determines the specificity in cargo selection and the destination of the vesicle. A transmembrane cargo protein, an Arf GTPase, and a coat protein (e.g. COPs, APs, or GGAs) are minimal components(More)
The demand for more computational power in science and engineering has spurred the design and deployment of ever-growing cluster systems. Even though the individual components used in these systems are highly reliable, the presence of large number of components inevitably increases the failure probability of such systems. Successful prediction of potential(More)
When a system fails to function properly, health-related data are collected for troubleshooting. However, it is challenging to effectively identify anomalies from the voluminous amount of noisy, high-dimensional data. The traditional manual approach is time-consuming, error-prone, and even worse, not scalable. In this paper, we present an automated(More)
Emerging evidences have indicated that long non-coding RNAs (LncRNAs) play vital roles in cancer development and progression. Previous studies have suggested that overexpression of SPRY4-IT1 predicates poor prognosis and promotes tumor progress in several cancers. However, the underlying mechanism of SPRY4-IT1 in bladder cancer remains unknown. In this(More)