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A 71-year-old man with diabetes mellitus visited our hospital with complaints of anorexia and weight loss (12 kg/3 months). He had megaloblastic anemia, cobalamin level was low, and autoantibody to intrinsic factor was positive. He was treated with intramuscular cyanocobalamin, and he was able to consume meals. GAD autoantibody and ICA were positive, and he(More)
In our auditory brainstem response (ABR) tests, a peculiar V-shaped negative wave at around 3 4 ms latency was observed. At present, this acoustically evoked short latency negative response (ASNR) is poorly understood. In order to study its appearance and origin, the ABR data of 3104 tests during 1980-98 were reviewed. The ASNR was found only in profound(More)
Gastric adenocarcinoma of the fundic gland (chief cell-predominant type, GA-FG-CCP) is a rare variant of well-differentiated adenocarcinoma, and has been proposed to be a novel disease entity. GA-FG-CCP originates from the gastric mucosa of the fundic gland region without chronic gastritis or intestinal metaplasia. The majority of GA-FG-CCPs exhibit either(More)
Eye movements during closed eyes closely reflect changes of the arousal level during transition from wakefulness to sleep. Because they contain both rapid and slow eye movements (REM and SEM), it has been difficult to detect them automatically. Hiroshige recently developed the method of linear regression analysis for automatic detection of the two types of(More)
Changes in cochlear blood flow (CoBF) and auditory brainstem response (ABR) in a pressure-induced animal model of acoustic neuroma were examined. A suboccipital approach was used to expose the right cerebello-pontine angle in guinea pigs. Under surgical microscope, the bundle of nerves and vessels at the entrance of the internal auditory meatus was exposed(More)
We herein describe the case of a 68-year-old man who developed overt diabetes mellitus following the topical administration of dexamethasone 0.1%-containing ointment over a five-month period to treat oral lichen planus. The topical dexamethasone therapy was discontinued gradually, and the patient was subsequently treated with insulin for one month without(More)
This is the first case report of exacerbation of tracheobronchitis due to nontoxigenic coryne-bacterium diphtheriae in which tracheal pseudomembrane was identified and oral erythromycine therapy was very successful. A 54-year-old womanwas admitted to our hospital on February 7, 1 994, with persistent productive cough, sore throat, and bloody sputum. She had(More)
To determine the degree of decrease in cochlear blood flow (CoBF) which causes compound action potentials (CAPs) to disappear, a cochlear ischemic model was created by compressing the internal auditory artery in guinea pig. CoBF was measured with a laser Doppler flowmeter, and CAPs were recorded with an electrode placed on the round window membrane. The(More)
The two nap sleep test (TNST) was developed and its usefulness for detecting sleepiness in long-distance drivers has been reported. This study's authors attempted to apply the TNST as a clinical test of sleepiness. A normal control group (n = 29), an obstructive sleep apnea syndrome (OSAS) group (n = 9), and another sleep disorder group (n = 6)(More)
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