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Deficiency of quorum sensing system inhibits the resistance selection of Pseudomonas aeruginosa to ciprofloxacin and levofloxacin in vitro.
OBJECTIVES The objective was to investigate how deficient of quorum sensing system (QS) affects minimal inhibitory concentrations (MICs) of Pseudomonas aeruginosa strains to ciprofloxacin (CIP) and
The effect of the sub-minimal inhibitory concentration and the concentrations within resistant mutation window of ciprofloxacin on MIC, swimming motility and biofilm formation of Pseudomonas
TLDR
The effect of CIP on MICs, swimming motility and biofilm formation of P.aeruginosa was quite different and the genes expression of rhlR and pqsR had a middle level positive correlation with the promotion of the swimming motilty.
Mutations in gyrB play an important role in ciprofloxacin-resistant Pseudomonas aeruginosa
TLDR
CIP was more competent than LEV in making P. aeruginosa resistant to in vitro selection and also to investigate the effect of time and concentration on mutations in resistance genes.
Drug resistance of Pseudomonas aeruginosa in vitro evoked by fluoroquinolones
Objective To observe and compare the resistance changes of ciprofloxacin (CIP), levofloxacin (LEV), norfloxacin (NOR) to Pseudomonas aeruginosa (PA), and choose the drug which had the best curative