Yasutaka Hoshino

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Infectious Diseases, National Institutes of Health (NIH). The NIH has patents, pending patent applications, and a license for rhesus and rhesus-human rotavirus reassortant vaccines; patents, pending patent applications, and licenses for human-bovine (UK) rotavirus reassortant vaccines; a patent for cold-adapted human rotavirus vaccines; and a pending patent(More)
There is an urgent need for a rotavirus vaccine, because up to 592,000 infants and young children <5 years old die each year from rotavirus diarrhea, predominantly in the developing countries. We have developed a tetravalent human-bovine rotavirus (UK) reassortant vaccine with VP7 (G) specificity for serotypes 1, 2, 3, and 4, which has been shown to be(More)
Actinoplanes missouriensis Couch 1963 is a well-characterized member of the genus Actinoplanes, which is of morphological interest because its members typically produce sporangia containing motile spores. The sporangiospores are motile by means of flagella and exhibit chemotactic properties. It is of further interest that members of Actinoplanes are(More)
BACKGROUND It is universally acknowledged that genome segment 4 of group A rotavirus, the major etiologic agent of severe diarrhea in infants and neonatal farm animals, encodes outer capsid neutralization and protective antigen VP4. RESULTS To determine which genome segment of three group A equine rotavirus strains (H-2, FI-14 and FI-23) with P[12](More)
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