Yasushi Kikuchi

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The utility of various synthetic peptides has been investigated in clinical trials of the treatment of cancers, infectious diseases and endocrine diseases. In the process of functional gene screening with in silico analysis for molecules with angiogenic properties, we generated a small peptide, angiogenic peptide (AG)-30, that possesses both antimicrobial(More)
In 1975 one of the coauthors, Ikebe, showed that the problem of computing the zeros of the regular Coulomb wave functions and their derivatives may be reformulated as the eigenvalue problem for infinite matrices. Approximation by truncation is justified but no error estimates are given there. The class of eigenvalue problems studied there turns out to be(More)
High-mobility group box 1 (HMGB1) mobilizes platelet-derived growth factor receptor alpha-positive (PDGFRα(+)) mesenchymal cells from bone marrow (BM) into circulation. However, whether HMGB1-induced endogenous PDGFRα(+) mesenchymal cells stimulate skin regeneration has been unclear. Here, we investigated the functions of the HMGB1/BM-PDGFRα(+) mesenchymal(More)
In this paper, it is first given as a necessary and sufficient condition that infinite matrices of a certain type have double eigenvalues. The computation of such double eigenvalues is enabled by the Newton method of two variables. The three-term recurrence relations obtained from its eigenvalue problem (EVP) subsume the well-known relations of (A) the(More)
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