Yasuo Morita

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Measurement of cerebrovascular reserve capacity predicts the risk of ischemic insult in patients with major vessel occlusion. Blood oxygenation level-dependent (BOLD) imaging has the potential to estimate reserve capacity of the cerebral circulation noninvasively based on changes in the signal that reflect differences in the magnetic susceptibility of(More)
A new series of succinate-based dual inhibitors against matrix metalloproteinases (MMPs) and tumor necrosis factor alpha converting enzyme (TACE) possessing highly-water solubility was designed, synthesized, and evaluated for enzyme inhibition. Incorporating of acidic or basic functional groups at the P(2)' position afforded sufficient water solubility(More)
Fibroblast collagenase (MMP-1), a member of the matrix metalloproteinases family, is believed to be a pathogenesis of arthritis, by cleaving triple-helical type II collagen in cartilage. From the similarity of the active site zinc binding mode with hydroxamate, we designed and synthesized alpha-mercaptocarbonyl possessing compounds (3-5), which incorporated(More)
This research is motivated by the following theme originated with H. Friedman: very often, if a theorem τ of ordinary mathematics is proved from the “right” set existence axioms, τ is equivalent to those axioms over some weaker system in which τ itself is not provable. This theme is referred to as Reverse mathematics. Here, we focus on three subsystems(More)
A duality theorem of projective and inductive limit spaces over a nonspherically complete valued field is obtained under a certain condition, and topologies of spaces of locally analytic functions are ¿studied. Introduction. Morita obtained in |5| a duality theorem of projec­ tive limit spaces and inductive limit spaces over a spherically complete(More)
December 5 December 8, 2006 Toki-city, Japan The 16th International Toki Conference “Advanced Imaging and Plasma Diagnostics” is the continuation of an annual series that was originally started in 1989, when the National Institute for Fusion Science was established. Each year, selected topics in plasma physics and fusion engineering research have been(More)
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