Yasunari Michinaka

Learn More
A recently identified Δ6 fatty acid desaturase in Mucor rouxii shows a low sequence homology (~24% at the amino acid level) to that isolated from Mortierella alpina, but is phylogenetically closer to a plant enzyme, suggesting the occurrence of Δ6 desaturase isozymes in Mucorales molds. In the present study, two types of Δ6 desaturases, mcD6-1 (Mo. alpina(More)
To elucidate the molecular mechanism governing fatty acid transport across the cell membrane, we first isolated a Saccharomyces cerevisiae mutant, B-1, that exhibits a reduced acyl-CoA oxidase activity and an increase in free fatty acid accumulation. Following mutagenesis of B-1, a mutant, YTS51, which secretes free fatty acids, was isolated. The(More)
  • 1