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Clinical reports indicate that the fluoroquinolone group of antibiotics can induce cutaneous photosensitivity reactions. In the present study, phototoxicity and photoallergenicity of quinolones including nalidixic acid (NA) norfloxacin (NFLX), ofloxacin (OFLX), enoxacin (ENX), ciprofloxacin (CPFX), lomefloxacin (LFLX), and tosufloxacin (TFLX) were(More)
To investigate the effects of Benzo[a]pyrene (B[a]P) and polychlorinated biphenyls (PCB) on in vitro cytokine production, we isolated cervical lymph node cells from ovalbumin (OA)-primed mice and the lymph node cells were cultured with various concentrations of B[a]P or PCB in the presence of antigen presenting cells (APC) and OA. B[a]P significantly(More)
We report an autopsy case of dementia associated with amyotrophic lateral sclerosis (ALS) in a 73-year-old female. She developed memory impairment at the age of 68 years. Atrophy of her hand muscles was noted at the age of 71 years. She was not aware of her memory impairment or muscle weakness, and was loquacious and euphoric. She was clinically diagnosed(More)
In male and female dd-mice at 4, 7, and 14 weeks of age and in 7- and 14-week-old mice gonadectomized at 4 weeks of age, the number of osteoclasts and the number and size of bone resorption areas along the surface of bone trabeculae in the distal metaphysis of the femur were determined. Osteoclasts were counted at the light-microscopic level in paraffin(More)
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