Yasuhiro Shiokawa

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PURPOSE We evaluated the safety and efficacy of long-term administration of dexmedetomidine in patients in the intensive care unit (ICU). Primary endpoint was the incidence of hypotension, hypertension, and bradycardia. Secondary endpoints were withdrawal symptoms, rebound effects, the duration of sedation with Richmond Agitation-Sedation Scale (RASS) ≤ 0(More)
Volatile anesthetics are generally considered to possess a vasodilator action. Some of their actions on pulmonary vessels, however, are not clearly understood. We examined the effects of various volatile anesthetics on pulmonary vessels using an in situ rabbit isolated-lung perfusion model. We prepared a rabbit constant-flow lung-perfusion model by sending(More)
Keywords Anti-NMDAR encephalitis Á Image diagnosis To the Editor: Anti-N-methyl-D-aspartate-receptor (NMDAR) enceph-alitis is caused by serum antibodies against NMDAR, and is often associated with tumors [1]. Its symptoms include psychosis, seizures and disturbance of consciousness, all of which resemble the symptoms induced by NMDA antagonists , such as(More)
A 69-year-old male patient with esophageal cancer underwent video assisted subtotal esophagectomy after neoadjuvant chemotherapy and radiation (50 Gy). Adhesion between esophagus and the aorta was so severe that the aortic arch was damaged and massive bleeding occurred during manipulation of the esophagus. However, as we had expected and prepared for the(More)
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