Yasuhiro Shiokawa

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Volatile anesthetics are generally considered to possess a vasodilator action. Some of their actions on pulmonary vessels, however, are not clearly understood. We examined the effects of various volatile anesthetics on pulmonary vessels using an in situ rabbit isolated-lung perfusion model. We prepared a rabbit constant-flow lung-perfusion model by sending(More)
Congenital afibrinogenemia is a rare autosomal recessive hemorrhagic disorder, and thrombotic complications occurring spontaneously or after infusion of fibrinogencontaining preparations have been reported in afibrinogenemic patients [1]. We report a case of mesenteric venous thrombosis due to fibrinogen replacement in a patient with congenital(More)
We evaluated the safety and efficacy of long-term administration of dexmedetomidine in patients in the intensive care unit (ICU). Primary endpoint was the incidence of hypotension, hypertension, and bradycardia. Secondary endpoints were withdrawal symptoms, rebound effects, the duration of sedation with Richmond Agitation-Sedation Scale (RASS) ≤ 0 relative(More)
The effect of preanesthetic 20 mg of famotidine on gastric fluid volume and pH were studied in patients scheduled for elective surgery. One hundred and twenty-eight patients were divided into four groups-control, intravenous, intramuscular and oral with 32 patients in each group. Patients in placebo group received no famotidine and served as control.(More)
•There are many reports on complication of tracheal intubation, but the development of acute respiratory distress associated with subcutaneous emphysema, pneumomediastinum and bilateral pneumothorax is a rare complication during general anesthesia. It has also been reported that tracheal perforation may be predisposed to such complication1-5. This is a(More)
A 69-year-old male patient with esophageal cancer underwent video assisted subtotal esophagectomy after neoadjuvant chemotherapy and radiation (50 Gy). Adhesion between esophagus and the aorta was so severe that the aortic arch was damaged and massive bleeding occurred during manipulation of the esophagus. However, as we had expected and prepared for the(More)
To the Editor: Anti-N-methyl-D-aspartate-receptor (NMDAR) encephalitis is caused by serum antibodies against NMDAR, and is often associated with tumors [1]. Its symptoms include psychosis, seizures and disturbance of consciousness, all of which resemble the symptoms induced by NMDA antagonists, such as ketamine. We report a patient with antiNMDAR(More)
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