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A new series of benzoxazole 2,4-thiazolidinediones was synthesized and evaluated for hypoglycemic activity in genetically obese and diabetic yellow KK mice. 2-Arylmethyl- and 2-(heteroarylmethyl)benzoxazole derivatives showed far more potent activity than known 2,4-thiazolidinedione derivatives such as ciglitazone, troglitazone and pioglitazone. A facile(More)
The electron addition spectrum A+(k,omega) is obtained analytically for the one-dimensional (1D) supersymmetric t-J model with 1/r2 interaction. The result is obtained first for a small-sized system and its validity is checked against the numerical calculation. Then the general expression is found which is valid for arbitrary size of the system. The(More)
The effects of oral administration of methyl (+) (3S)-1,2,3,4-tetrahydro-3-hydroxymethyl-beta-carboline-2-carbodithioa te (THC) on protein synthesis in the liver and chronic liver injury induced by carbon tetrachloride (CCl4) in rats were studied. THC increased liver weight and the contents of protein and ribonucleic acid, but not deoxyribonucleic acid, in(More)