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- Masafumi Shimizu, Yoshiko Nakagawa, +5 authors Hitoshi Kunoh
- Journal of General Plant Pathology
- 2000
To survey endophytic actinomycetes as potential biocontrol agents against fungal diseases of rhododendron, young plants of rhododendron were surface-sterilized for use as an isolation source. Nine,… (More)
- Hiroyasu Onaka, Shin-ichi Taniguchi, Yasuhiro Igarashi, Tamotsu Furumai
- The Journal of antibiotics
- 2002
Staurosporine is a representative member of indolocarbazole antibiotics. The entire staurosporine biosynthetic and regulatory gene cluster spanning 20-kb was cloned from Streptomyces sp. TP-A0274 and… (More)
- Yoshifumi Tamura, Yasushi Tanaka, +12 authors Ryuzo Kawamori
- The Journal of clinical endocrinology and…
- 2005
Insulin resistance is associated with the circulating free fatty acid (FFA) level and intracellular lipid content in muscle and liver. We investigated the effect of 2-wk diet and exercise therapy on… (More)
- Hiroyasu Onaka, Yukiko Mori, Yasuhiro Igarashi, Tamotsu Furumai
- Applied and environmental microbiology
- 2011
Natural products produced by microorganisms are important starting compounds for drug discovery. Secondary metabolites, including antibiotics, have been isolated from different Streptomyces species.… (More)
Heat transfer of single-walled carbon nanotubes (SWNTs) in practical situations is investigated using molecular dynamics (MD) simulations. Attenuation of the expected high thermal conductivity was… (More)
- Hiroyasu Onaka, Shin-ichi Taniguchi, Yasuhiro Igarashi, Tamotsu Furumai
- Bioscience, biotechnology, and biochemistry
- 2003
The biosynthetic gene cluster for rebeccamycin, an indolocarbazole antibiotic, from Lechevalieria aerocolonigenes ATCC 39243 has 11 ORFs. To clarify their functions, mutants with rebG, rebD, rebC,… (More)
- Yasuhiro Igarashi, Martha E. Trujillo, +7 authors Tamotsu Furumai
- Bioorganic & medicinal chemistry letters
- 2007
Two novel anthraquinones, lupinacidins A (1) and B (2), have been isolated from the culture broth of a new endophytic actinomycete belonging to the genus Micromonospora. Lupinacidins were found to… (More)
- Masafumi Shimizu, Norikazu Fujita, +6 authors Hitoshi Kunoh
- Journal of General Plant Pathology
- 2001
An endophytic actinomycete, Streptomyces sp. R-5, which had been isolated from a field-grown rhododendron plant, was used to protect rhododendron seedlings in tissue culture from Pestalotia disease… (More)
- Takashi Nomiyama, Yasuhiro Igarashi, +11 authors Hirotaka Watada
- Biochemical and biophysical research…
- 2004
Inducible nitric oxide synthetase plays an essential role in insulin resistance induced by a high-fat diet. The reaction of nitric oxide with superoxide leads to the formation of peroxynitrite… (More)
- Yasuhiro Igarashi, Saeko Yanase, +5 authors Shigefumi Kuwahara
- Journal of natural products
- 2011
A new anthraquinone derivative, lupinacidin C (1), was isolated from the endophytic actinomycete Micromonospora lupini. The structure was elucidated on the basis of spectroscopic analyses, and the… (More)