Yasuhiro Horibata

Identification and characterization of human ethanolaminephosphotransferase1.

Yasuhiro Horibata, Yoshio Hirabayashi
Journal of lipid research
2007

CDP-ethanolamine:diacylglycerol ethanolaminephosphotransferase (EPT) catalyzes the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to produce phosphatidylethanolamine (PE). To… (More)

StarD7 mediates the intracellular trafficking of phosphatidylcholine to mitochondria.

Yasuhiro Horibata, Hiroyuki Sugimoto
The Journal of biological chemistry
2010

Steroidogenic acute regulatory protein-related lipid transfer (START) domains, found in 15 mammalian proteins termed StarD1-StarD15, are lipid-binding domains implicated in the intracellular lipid… (More)

Unique catabolic pathway of glycosphingolipids in a hydrozoan, Hydra magnipapillata, involving endoglycoceramidase.

Yasuhiro Horibata, Keishi Sakaguchi, +5 authors Makoto Ito
The Journal of biological chemistry
2004

Endoglycoceramidase (EGCase; EC 3.2.1.123) is an enzyme capable of cleaving the glycosidic linkage between oligosaccharides and ceramides of various glycosphingolipids. We detected strong EGCase… (More)

Low-density lipoprotein and oxysterols suppress the transcription of CTP: Phosphoethanolamine cytidylyltransferase in vitro.

Hiromi Ando, Yasuhiro Horibata, Satoko Yamashita, Tetsunari Oyama, Hiroyuki Sugimoto
Biochimica et biophysica acta
2010

The rate-limiting step in phosphatidylethanolamine (PE) synthesis by the CDP-ethanolamine pathway is the second step, which is catalyzed by CTP:phosphoethanolamine cytidylyltransferase (ET). The… (More)

Phosphatidylglucoside exists as a single molecular species with saturated fatty acyl chains in developing astroglial membranes.

Yasuko Nagatsuka, Yasuhiro Horibata, +6 authors Yoshio Hirabayashi
Biochemistry
2006

We previously found that phosphatidylglucoside (PtdGlc), a novel glycolipid expressed in HL60 cells, plays a role in forming signaling microdomains involved in cellular differentiation. Because cells… (More)

A sensitive and reproducible assay to measure the activity of glucosylceramide synthase and lactosylceramide synthase using HPLC and fluorescent substrates.

Yasuhiro Hayashi, Yasuhiro Horibata, Keishi Sakaguchi, Nozomu Okino, Makoto Ito
Analytical biochemistry
2005

Glucosylceramide synthase (GlcT) and lactosylceramide synthase (GalT) are key enzymes for the synthesis of major glycosphingolipids of vertebrates. In this article, we report a new reliable method to… (More)

Enzymatic and transcriptional regulation of the cytoplasmic acetyl-CoA hydrolase ACOT12.

Yasuhiro Horibata, Hiromi Ando, Masahiko Itoh, Hiroyuki Sugimoto
Journal of lipid research
2013

Acyl-CoA thioesterase 12 (ACOT12) is the major enzyme known to hydrolyze the thioester bond of acetyl-CoA in the cytosol in the liver. ACOT12 contains a catalytic thioesterase domain at the N… (More)

Fucoganglioside α-fucosyl(α-galactosyl)-GM1: a novel member of lipid membrane microdomain components involved in PC12 cell neuritogenesis

In order to search for novel components of lipid membrane microdomains involved in neural signalling pathways, mAbs (monoclonal antibodies) were raised against the detergent-insoluble membrane… (More)

StarD7 Protein Deficiency Adversely Affects the Phosphatidylcholine Composition, Respiratory Activity, and Cristae Structure of Mitochondria.

Yasuhiro Horibata, Hiromi Ando, +5 authors Hiroyuki Sugimoto
The Journal of biological chemistry
2016

Phosphatidylcholine (PC) is a major phospholipid of mitochondria, comprising 40-50% of both the outer and the inner membranes. However, PC must be imported from its production organelles because… (More)

Sensitivity of phosphatidylglucoside against phospholipases.

Yasuhiro Horibata, Yasuko Nagatsuka, Peter Greimel, Yukishige Ito, Yoshio Hirabayashi
Analytical biochemistry
2007

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