Yasuhiro Gotoh

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Q |f − fQ|dx < ∞, (1) where |Q| is the n-dimensional Lebesgue measure of Q, fQ = |Q|−1 ∫ Q fdx, and the supremum is taken over all closed cubes Q ⊂ D with sides parallel to the coordinate axes. Let D and D′ be subdomains of Rm and Rn, m, n ≥ 1, respectively. We say that a map F : D → D′ is measurable if F−1(E) is measurable for each measurable subset E of(More)
BACKGROUND The introduction of a guidewire through bile duct strictures may facilitate transpapillary bile duct biopsy and subsequent biliary drainage. METHODS Endoscopic bile duct biopsy was attempted in 61 patients with bile duct strictures. After the introduction of a guidewire into the bile duct, biopsy forceps were inserted via the papilla. Both(More)
Escherichia albertii is a recently recognized close relative of Escherichia coli. This emerging enteropathogen possesses a type III secretion system (T3SS) encoded by the locus of enterocyte effacement, similar to enteropathogenic and enterohemorrhagic E. coli (EPEC and EHEC). Shiga toxin-producing strains have also been identified. The genomic features of(More)
Technical Appendix Technical Appendix Figure. Distribution of the MICs of colistin for the 684 E. coli isolates from diseased swine in Japan between 1991 and 2014. Because the breakpoint MIC of colistin for Enterobacteriaceae has not yet been published by the CLSI (1), isolates with an MIC of ≥4 μg/ml were considered colistin resistant according to the(More)
Enterohemorrhagic E. coli (EHEC) causes diarrhea and hemorrhagic colitis with life-threatening complications, such as hemolytic uremic syndrome. Their major virulence factor is Shiga toxin (Stx), which is encoded by bacteriophages. Of the two types of Stx, the production of Stx2, particularly that of Stx2a (a subtype of Stx2), is a major risk factor for(More)
A previously developed passively operating transmission capable of switching its reduction ratio in response to load torque was further developed into a non-contact load-responsive transmission. The reduction ratio is switched by a non-contact magnetic clutch that responds to the load torque using a passive magnetic mechanism without any accessory(More)
Bacteriophages are fascinating genetic elements that play key roles in the evolution and diversification of bacterial genomes. Shiga toxin (Stx)-transducing phages are important genetic elements that disseminate the stx genes among enterohemorrhagic Escherichia coli (EHEC). They are generally regarded as lambda-like phages, but their biological and genetic(More)
Enteropathogenic Escherichia coli (EPEC) induce attaching and effacing (A/E) lesions in enterocytes and produce the bundle-forming pilus (BFP) contributing to the localized adherence (LA) pattern formation on HeLa cells. Enteroaggregative E. coli (EAEC) produce aggregative adherence (AA) on HeLa cells and form prominent biofilms. The ability to produce LA(More)
Rickettsiae are obligate intracellular bacteria that have small genomes as a result of reductive evolution. Many Rickettsia species of the spotted fever group (SFG) cause tick-borne diseases known as "spotted fevers". The life cycle of SFG rickettsiae is closely associated with that of the tick, which is generally thought to act as a bacterial vector and(More)