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OBJECTIVE To study the effect of Lichong Decoction (Lichong Decoction for strengthening anti-pathogenic Qi and eliminating blood stasis) on the expression of insulin-like growth factor-I (IGF-I) and proliferating cell nuclear antigen (PCNA) mRNA in a rat model of uterine leiomyoma. METHODS Fifty female Wistar rats were randomized into a normal control(More)
INTRODUCTION The limited information for effects of serum trace elements and genetic polymorphisms on lung cancer is available. Based on a hospital based case-control study, the epidemiological questionnaires were completed by face to face interview, and the gene polymorphisms were tested by RFLP-PCR, and serum trace metals were measured by atomic(More)
—This study examined the relationship between socioeconomic and demographic attributes of local residents and their attitudes toward tourism in Washington, NC, a small community where tourism is in its development stage. Residents' attitudes toward tourism were measured by adapting 20 items from the Tourism Impact Attitude Scale developed by Lankford and(More)
An SOD-type metalloaluminophosphate molecular sieve (denoted as SOD-Mn) was ionothermally synthesized by introducing manganese(II) cations into the reaction mixture via MnO-acid or MnO2-reductant reactions. Composition and structure analyses results show that two kinds of manganese(II) cations exist in the SOD-Mn structure. Part of the manganese(II) cations(More)
Epigenetic events, a key driving force in the development of lung cancer, two changes integral to epigenetic transcriptional control are DNA methylation and covalent modification of histone proteins. Aberrant methylation may be the most common mechanism of inactivating cancer-related genes in lung cancer, and histone modification may be closely associated(More)
OBJECTIVE To study the effect of Lichong decoction (LD) on expression of matrix metalloproteinase- 2 (MMP-2) and metalloproteinase-2 (TIMP-2) in a rat model of uterine leiomyoma (UL). METHODS UL was induced in rats using exogenous estrogen and progesterone. LD was administered (p.o.) for 4 weeks, and mifepristone (RU-486) used as a control. To observe the(More)
OBJECTIVE To study on effects of Lichong decoction on expression of apoptosis-controlling genes, Bcl-2 and Bcl-2-associated X protein (Bax) mRNAs in hysteromyoma tissue of the hysteromyoma model rat. METHODS Fifty Wistar female rats were randomly divided into a normal group, a model group, a Lichong decoction group, a Guizifuling capsule group and a(More)
iii ACKNOWLEDGMENTS My sincere gratitude goes first to my advisor, Professor Noah Sobe, for his guidance and assistance through my graduate study. I would also like to thank Professor Kate Phillippo, for agreeing to join my thesis approval committee, also for her wonderful teaching in the Sociology of Education. I would also like to express my deep(More)
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