Yasmin Sultana

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Pefloxacin mesylate is a flouroquinolone antibacterial drug effective in the treatment of bacterial conjunctivitis. The objective of the present work was to develop ocular inserts of pefloxacin mesylate and evaluate their potential for sustained ocular delivery. Reservoir-type ocular inserts were prepared by the film casting technique in teflon coated Petri(More)
OBJECTIVE A simple, precise, and stability indicating high performance liquid chromatography (HPLC) method was developed and validated for the simultaneous determination of propranolol hydrochloride and valsartan in pharmaceutical dosage form. MATERIALS AND METHODS The method involves the use of easily available inexpensive laboratory reagents. The(More)
It is common knowledge that the ocular bioavailability and therapeutic response of drugs applied topically as eye drops is very poor, this is due to rapid precorneal drainage of the instilled dose, which could be overcome by the use of in-situ gelling systems that undergo a sol-gel transition in the cul-de-sac. This work describes the ophthalmic formulation(More)
Glial cells are integrated part of neurovascular unit of blood brain barrier (BBB). They undergo mitosis and mainly classified as astrocytes, oligodendrocytes, microglia, ependymal cells and nerve glial antigen 2 cells. Being a most versatile glial cell, astrocytes provide structural support to neurons, maintain brain homeostasis, take part in neuronal(More)
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